Objective: To analyze the epidemiologic characteristics and etiology of hand-foot-mouth disease in Sichuan Neijiang from 2010 to 2017

and to discuss the problems existing in the prevention and control of the disease

so as to provide reference for the prevention and control of hand-foot-mouth disease. Methods: Descriptive epidemio-logical method was adopted

analysis of epidemic data of hand-foot-mouth disease in Neijiang from 2010 to 2017 were conducted by using Excel 2003 software. Results: From 2010 to 2017

a total of 15

113 cases of hand-foot-mouth disease were reported in Neijiang

with an annual incidence of 19.53/100

000 to 67.66/100

000

with an average of 50.05/100

000. The peak incidence of infection was in 2012

with an annual incidence of 67.66/100

000. The main morbidity population was aged from 0 to 5 years old

accounting for 94.81% of the total number. Children in diaspora and childcare accounted for 98.13% of the total number in the occupational distribution. The time of onset mainly distributed from Apr. to Jul. and Oct. to Dec. throughout the year. From 2010 to 2017

a total of 4

012 cases of blood samples were collected from children with hand-foot-mouth disease

and 2

390 cases (59.57%) were positive for viral nucleic acid tests

of which EV71 accounted for 28.83% (689/2

390)

CA16 accounted for 27.24% (651/2

390)

and other enteric viruses accounted for 43.93% (1

050/2

390). Conclusion: The incidence of hand-foot-mouth disease is at a relatively high level in Neijiang

it is distributed throughout the year and mainly concentrated in children aged from 0 to 5 years. In order to control the spread and prevalence of hand-foot-mouth disease

it is necessary to strengthen the monitoring and publicity

expand the population immunized by vaccine

and increase the pathogen spectrum protected by vaccine.