Relationship among the level of lipoprotein(a),fibrinogen,D-dimer and carotid atherosclerosis in patients with cerebral infarction

KONG Xiang-feng; WANG Ping; CHEN Ming

doi:10.13406/j.cnki.cyxb.2011.09.027

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Relationship among the level of lipoprotein(a),fibrinogen,D-dimer and carotid atherosclerosis in patients with cerebral infarction

更新时间：2024-01-17

- Relationship among the level of lipoprotein(a),fibrinogen,D-dimer and carotid atherosclerosis in patients with cerebral infarction
- Journal of Chongqing Medical University Vol. 36, Issue 9, Pages: 1101-1102(2011)
- 作者机构：
  
  新疆医科大学第五附属医院神经内科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2011.09.027
  CLC： R743.32
- Published：2011，
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[1]孔祥锋,王萍,陈明.脂蛋白(a)与脑梗死患者颈动脉粥样硬化、纤维蛋白原、D-二聚体的关系[J].重庆医科大学学报,2011,36(09):1101-1102.

KONG Xiang-feng, WANG Ping, CHEN Ming. Relationship among the level of lipoprotein(a),fibrinogen,D-dimer and carotid atherosclerosis in patients with cerebral infarction. [J]. Journal of Chongqing Medical University 36(9):1101-1102(2011)
[1]孔祥锋,王萍,陈明.脂蛋白(a)与脑梗死患者颈动脉粥样硬化、纤维蛋白原、D-二聚体的关系[J].重庆医科大学学报,2011,36(09):1101-1102. DOI： 10.13406/j.cnki.cyxb.2011.09.027.

KONG Xiang-feng, WANG Ping, CHEN Ming. Relationship among the level of lipoprotein(a),fibrinogen,D-dimer and carotid atherosclerosis in patients with cerebral infarction. [J]. Journal of Chongqing Medical University 36(9):1101-1102(2011) DOI： 10.13406/j.cnki.cyxb.2011.09.027.

摘要

目的:探讨脑梗死患者脂蛋白（a）[Lipoprotein（a）

LP（a）]与颈动脉粥样硬化、纤维蛋白原、D-二聚体关系。方法:入选185例脑梗死患者

根据颈动脉彩色超声多普勒检查结果

分为无斑块组、不稳定斑块组、稳定斑块组

测定血清脂蛋白（a）、纤维蛋白原、D-二聚体水平并进行分析。结果:不稳定斑块组血清LP（a）水平显著高于稳定斑块组

P<0.01;脑梗死颈动脉粥样硬化斑块患者LP（a）与血清纤维蛋白原、D-二聚体呈正相关。结论:LP（a）增高与颈动脉易损斑块密切相关

临床通过测定LP（a）水平预测脑梗死的发病风险

对预防脑梗死以及有效减少脑梗死复发具有重要意义。

Abstract

Objective:To discuss the relationship among the level of lipoprotein(a)LP(a)

fibrinogen

D-dimer and carotid atherosclerosis in Patients with cerebral infarction.Methods:185 patients with cerebral infarction were divided into no-plaque group

unstable plaque group

stable plaque group with carotid ultrasonography.The levels of LP(a)

fibrinogen

D-dimer were measured.Then the relationship among the serum levels of LP(a)

fibrnogen

D-dimer and Carotid atherosclerosis was analyzed.Results:The serum level of LP(a) in unstable plaque group was higher than in stable plaque group(P<0.01);The levels of LP(a) was positively related to fibrinogen and D-dimer in the patients with carotid artery atherosclerosis.Conclusion:The increase of LP(a) is closely related to carotid unstable plaque.It have inportant clinical significance to prevent cerebral infarction and reduce it recurrence by detecting level of LP(a) to predict risk of cerebral infarction.

关键词

脂蛋白（a）纤维蛋白原D-二聚体颈动脉粥样硬化

Keywords

lipoprotein(a)fibrinogenD-dimercarotid atherosclerosis

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