Treatment and clinical analysis of hyponatremia after head injury

CHEN Yong; QIN Chuan; ZHANG Zheng-bao; HU Jian-gang; ZHANG Biao; YANG Xiu-jiang

doi:10.13406/j.cnki.cyxb.2011.09.020

您当前的位置：

首页 >

文章列表页 >

Treatment and clinical analysis of hyponatremia after head injury

更新时间：2024-01-17

- Treatment and clinical analysis of hyponatremia after head injury
- Journal of Chongqing Medical University Vol. 36, Issue 9, Pages: 1138-1140(2011)
- 作者机构：
  
  重庆市大足县人民医院神经外科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2011.09.020
  CLC： R651.15
- Published：2011，
扫描看全文
[1]陈勇,覃川,张正保,胡建刚,张彪,杨秀江.颅脑损伤后低钠血症的治疗及临床分析[J].重庆医科大学学报,2011,36(09):1138-1140.

CHEN Yong, QIN Chuan, ZHANG Zheng-bao, et al. Treatment and clinical analysis of hyponatremia after head injury. [J]. Journal of Chongqing Medical University 36(9):1138-1140(2011)
[1]陈勇,覃川,张正保,胡建刚,张彪,杨秀江.颅脑损伤后低钠血症的治疗及临床分析[J].重庆医科大学学报,2011,36(09):1138-1140. DOI： 10.13406/j.cnki.cyxb.2011.09.020.

CHEN Yong, QIN Chuan, ZHANG Zheng-bao, et al. Treatment and clinical analysis of hyponatremia after head injury. [J]. Journal of Chongqing Medical University 36(9):1138-1140(2011) DOI： 10.13406/j.cnki.cyxb.2011.09.020.

摘要

目的:探讨颅脑损伤后低钠血症的治疗。方法:回顾性分析238例颅脑损伤患者

根据治疗方式的不同分为早期补充浓氯化钠组和常规补液组

早期补浓氯化钠组107例采取电解质钠离子低于135 mmol/L时予3%浓氯化钠500 ml/d治疗

对照组131例采取常规补充生理需要量治疗

治疗后统计分析2组之间治疗结果差异。结果:早期补浓氯化钠组低钠血症纠正率明显高于对照组。结论:颅脑损伤患者当一旦出现低钠血症

立即予浓氯化钠治疗

能明显快速纠正低钠血症

且不会增加抗利尿激素异常分泌综合征（Syndrome of inappropriate antidiuretic hormone

SIADH）的发生率。

Abstract

Objective:To discuss the treatment and clinical characteristics of hyponatremia after brain trauma.Methods:238 patients with complicated hyponatremia after brain injury were enrolled in this retrospective study.According to treatment

all patients were divided into two groups:hypertonic saline solution injecting group(HSSI group) and control group.500 ml of 3% sodium chloride was injected per-day in 107 patients of HSSI group when serum sodium were lower than 135 mmol/L

and routine fluid infusion according to physiological requirement was performed in 131 patients of control group.Recovery rate and recurrence of hyponatremia were measured to be compared between two groups.Results:Recovery rate of serum sodium in HSSI group was significantly higher than that in control group.Conclusion:HSSI had a significant therapeutic effect on patients with complicated hyponatremia after traumatic brain injury;moreover

it did not increase the incidence of SIADH.

关键词

颅脑损伤低钠血症浓氯化钠治疗抗利尿激素异常分泌综合征

Keywords

head injuryhyponatremiasaline solutionsyndrome of inappropriate antidiuretic hormone(SIADH)

references

Views

108

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Efficacy and safety of tolvaptan for hyponatremia:a Meta-analysis

Clinical characteristics in tuberculous meningitis with hyponatremia

Related Author

Zhang Xiangyun

Du Shanshan

Zu Dongni

Zhao Mingyi

Yang Jingyu

Xiang Rongwu

Tang Siying

Jing Huan

Related Institution

Department of Clinical Pharmacy,School of Life Science and Biopharmaceutical,Shenyang Pharmaceutical University

Department of Endocrinology，The First Affiliated Hospital of Chongqing Medical University

⁰