Evaluation for biocompatibility of the biological zipper for the miniature pig

YU Chen-lin; LIU Zhi-xue; MA Lei; CAI Li-ping; XU Chen; CUI Shu-fang

doi:10.13406/j.cnki.cyxb.2011.09.008

您当前的位置：

首页 >

文章列表页 >

Evaluation for biocompatibility of the biological zipper for the miniature pig

更新时间：2024-01-17

- Evaluation for biocompatibility of the biological zipper for the miniature pig
- Journal of Chongqing Medical University Vol. 36, Issue 9, Pages: 1077-1080(2011)
- 作者机构：
  
  第二军医大学训练部实验动物中心
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2011.09.008
  CLC： R-331
- Published：2011，
扫描看全文
[1]余琛琳,刘志学,马雷,蔡丽萍,徐晨,崔淑芳.小型猪用生物拉链的生物相容性评价[J].重庆医科大学学报,2011,36(09):1077-1080.

YU Chen-lin, LIU Zhi-xue, MA Lei, et al. Evaluation for biocompatibility of the biological zipper for the miniature pig. [J]. Journal of Chongqing Medical University 36(9):1077-1080(2011)
[1]余琛琳,刘志学,马雷,蔡丽萍,徐晨,崔淑芳.小型猪用生物拉链的生物相容性评价[J].重庆医科大学学报,2011,36(09):1077-1080. DOI： 10.13406/j.cnki.cyxb.2011.09.008.

YU Chen-lin, LIU Zhi-xue, MA Lei, et al. Evaluation for biocompatibility of the biological zipper for the miniature pig. [J]. Journal of Chongqing Medical University 36(9):1077-1080(2011) DOI： 10.13406/j.cnki.cyxb.2011.09.008.

摘要

目的:研究设计小型猪腹壁拉链动物模型用生物拉链

并检测、评价其生物相容性。方法:结合小型猪体型和生活习性特点、以及动物外科手术实验要求

设计生物拉链外形

并依据国家标准（GB/T 16886.10-2005/ISO 10993-10:2002）

采用皮肤刺激性试验和皮肤致敏试验测定其生物相容性。结果:生物拉链具备操作简便、节省手术操作时间、减少创口感染等诸多优点

并成功获得国家知识产权专利（专利号:200920207646.1）;皮肤刺激性试验未出现皮肤刺激反应;皮肤致敏试验未出现皮肤致敏反应。结论:生物拉链设计合理

具有良好的生物相容性

为小型猪腹壁拉链模型动物在教学、科研和临床中的推广应用奠定了良好的基础。

Abstract

Objective:To design the biological zipper for the animal model of abdominal wall zipper of the miniature pig and test its biocompatibility.Methods:The shape of the biological zipper was designed in line with the size and living habits of the miniature pig

and the demands for animal surgery.According to the series standards of GB/T16886.10-2005

the skin irritation and the skin sensitization experiments were carried out on miniature pigs.Results:The constructed biological zipper was easy to operate

could save operation time and reduce wound infections

and it has successfully obtained the state intellectual property patent(patent number:200920207646.1).No irritation on the integral or damaged skin of miniature pig was observed.Sensitization effect on the skin of miniature pig was not found.Conclusion:The biological zipper with reasonable design and satisfactory biocompatibility lays a good foundation for the animal model of abdominal wall zipper of the miniature pig in teaching

research and clinical application.

关键词

生物拉链皮肤刺激皮肤致敏生物相容性

Keywords

biological zipperskin irritationskin sensitizationbiocompatibility

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Biocompatibility of graphene/nano-hydroxyapatite/polyamide 66 composite material

Study on the biocompatibility of semiconductor quantum dots to the rat dental papillae cells (RDPC) cultured in vitro

Biocompatibility of nanohydroxyapatite/polyamino acid composite

Related Author

Yang Qiming

Zhang Shiyang

Zhao Weikang

Jiang Dianming

SUN Deping

et al

陈睿

LI Jun

Related Institution

Department of Orthopedics,The First Affiliated Hospital of Chongqing Medical University

Department of Oral and Maxillofacial Surgery,the First Affiliated Hospital,Chongqing Medical University

重庆医科大学附属第一医院口腔颌面外科

Department of Orthopedics,the First Affiliated Hospital,Chongqing Medical University

四川大学纳米生物材料研究中心

⁰