The prognosis value of lactate clearance rates in patients with respiratory failure

LAI Yi

doi:10.13406/j.cnki.cyxb.2011.07.021

您当前的位置：

首页 >

文章列表页 >

The prognosis value of lactate clearance rates in patients with respiratory failure

更新时间：2024-01-17

- The prognosis value of lactate clearance rates in patients with respiratory failure
- Journal of Chongqing Medical University Vol. 36, Issue 7, Pages: 878-880(2011)
- 作者机构：
  
  贵州省人民医院干医科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2011.07.021
  CLC： R563.8
- Published：2011，
扫描看全文
[1]赖异.乳酸清除率在呼吸衰竭患者近期预后判定中的作用[J].重庆医科大学学报,2011,36(07):878-880.

LAI Yi. The prognosis value of lactate clearance rates in patients with respiratory failure. [J]. Journal of Chongqing Medical University 36(7):878-880(2011)
[1]赖异.乳酸清除率在呼吸衰竭患者近期预后判定中的作用[J].重庆医科大学学报,2011,36(07):878-880. DOI： 10.13406/j.cnki.cyxb.2011.07.021.

LAI Yi. The prognosis value of lactate clearance rates in patients with respiratory failure. [J]. Journal of Chongqing Medical University 36(7):878-880(2011) DOI： 10.13406/j.cnki.cyxb.2011.07.021.

摘要

目的:探讨乳酸清除率在呼吸衰竭患者预后判定中的作用。方法:检测83例呼吸衰竭患者12 h乳酸清除率。比较不同预后患者的临床特征

比较患者不同乳酸清除率对预后的影响

并采用Logistic回归分析多因素分析调整结果。结果:83例患者死亡17例（20.5%）。生存组和死亡组患者在性别、年龄、疾病种类等方面差异没有统计学意义（P

0.05）;而入院APACHEⅡ评分、pH值、PaO2、PaCO2、PaO2/FiO2及入院动脉血乳酸和12 h乳酸清除率差异均有统计学意义（P

0.05）。患者入院动脉血乳酸和入院pH值、PaO2、PaO2/FiO2均呈负相关

和入院PaCO2、APACHEⅡ评分均呈正相关

而12 h乳酸清除率和这些因素的相关性更为明显。高乳酸清除率组死亡率为13.0%

低清除率组死亡率为34.5%（χ2=5.365

P=0.021）。低清除率组较高清除率组发生死亡风险的OR值为3.534

95%CI为1.023

2.524。经Logistic回归多因素调整后

低清除率组较高清除率组发生死亡风险的OR值为2.782。结论:乳酸清除率可作为判断呼吸衰竭患者预后的一个重要指标。

Abstract

Objective: To investigate the prognosis value of lactate clearance rate in patients with respiratory failure.Methods:12 h lactate clearance rate was detected in 83 patients with respiratory failure.We used Logistic regression analysis for the prognosis.Results:A total of 17 patients died(20.5%).The sex

age

type of disease was not statistically significant between survival group and death group(P>0.05);the admission APACHE Ⅱ score

pH value

PaO2

PaCO2

PaO2/FiO2

admission blood lactate and lactic acid 12h clearance rate were significant differences between two groups(P<0.05).The blood lactate was negative correlated with pH value

PaO2

PaO2/FiO2

and positively correlated with PaCO2

APACHE Ⅱ

while the 12h lactate clearance rates were more apparent with these factors.The mortality in high lactate clearance rate group was 13.0%

Vs 34.5% in low clearance rate group(χ2=5.365

P= 0.021).The low-clearance group had a higher risk of mortality

OR= 3.534

95% CI was 1.023~12.524.After Logistic regression multivariate adjustment

the OR was 2.782.Conclusion: The rate of lactate clearance in patients with respiratory failure could be used as an important indicator for prognosis.

关键词

呼吸衰竭乳酸清除率预后

Keywords

respiratory failurelactate clearance rateprognosis

references

Views

102

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Anterior and posterior circulation infarction image score（APCIIS），a novel approach to evaluate the prognosis of patients with acute ischemic stroke

Diagnostic and prognostic value of muscle echogenicity combined with plasma inflammatory factors for intensive care unit-acquired weakness

Comparison of efficacy and complications of endoscopic surgery through three different approaches in the treatment of thyroid microcarcinoma

Identification of shared genetic features and molecular mechanisms of metabolic syndrome and colorectal cancer based on transcriptomic data

Effect of GluA1 interacting proteins GNAI2 and SRSF10 on prognosis of Hepatocellular carcinoma and establishment of diagnostic model

Related Author

Peng Shixin

Qiu Yulong

Zhu Ji

Zhang Xiaodong

Jiang Li

Xu Rui

Chen Jing

Zhu Jie

Related Institution

Department of Neurosurgery，The First Affiliated Hospital of Chongqing Medical University

Department of Ultrasound，Chongging Emergency Medical Center

Department of Neurology ， Chongging Emergency Medical Center

Intensive Care Unit，Chongging Emergency Medical Center

Department of Respiratory Medicine，Chongging Emergency Medical Center

⁰