Clinical feature and therapy effect analysis of 16 cases of critical A H1N1 influenza

ZHOU Jing; XU Fei; ZHANG Wei

doi:10.13406/j.cnki.cyxb.2011.07.015

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Clinical feature and therapy effect analysis of 16 cases of critical A H1N1 influenza

更新时间：2024-01-17

- Clinical feature and therapy effect analysis of 16 cases of critical A H1N1 influenza
- Journal of Chongqing Medical University Vol. 36, Issue 7, Pages: 883-885(2011)
- 作者机构：
  
  南昌大学第一附属医院呼吸内科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2011.07.015
  CLC： R511.7
- Published：2011，
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[1]周菁,许飞,张伟.16例甲型H1N1流感危重症确诊病例临床特征及治疗情况分析[J].重庆医科大学学报,2011,36(07):883-885.

ZHOU Jing, XU Fei, ZHANG Wei. Clinical feature and therapy effect analysis of 16 cases of critical A H1N1 influenza. [J]. Journal of Chongqing Medical University 36(7):883-885(2011)
[1]周菁,许飞,张伟.16例甲型H1N1流感危重症确诊病例临床特征及治疗情况分析[J].重庆医科大学学报,2011,36(07):883-885. DOI： 10.13406/j.cnki.cyxb.2011.07.015.

ZHOU Jing, XU Fei, ZHANG Wei. Clinical feature and therapy effect analysis of 16 cases of critical A H1N1 influenza. [J]. Journal of Chongqing Medical University 36(7):883-885(2011) DOI： 10.13406/j.cnki.cyxb.2011.07.015.

摘要

目的:综合分析甲型H1N1流感危重症的临床特征和治疗效果。方法:动态观察16例确诊甲型H1N1流感危重症病例的临床特征

对诊治情况进行回顾性分析。结果:16例危重症患者中

男性6例

女性10例

16例均发生肺部感染

所有患者均有发热

平均发热持续3.64 d入院

咳嗽、乏力、肌肉酸痛、胸闷、恶心等全身症状较多;早期的抗病毒治疗及短期3

d的小剂量糖皮质激素及晚期的提高免疫力治疗及广谱包括真菌的抗菌药物使用在部分病例中获得成功

多科医生及护士的密切合作和精细治疗十分重要。结论:甲型H1N1流感病毒致病力及致死率与季节性流感相似

危重症需要早期的抗病毒治疗和后期的抗菌治疗及精细的加强治疗以提高存活率。

Abstract

Objective:To conduct aggregate analysis of the clinical features and therapy effects of critical A H1N1 influenza cases.Methods:The clinical features of 16 cases of critical A H1N1 influenza were dynamically observed

and the therapy effects were retrospectively analyzed.Results:In the 16 cases

6 were male and the others were female;all of the 16 cases had lung infection.All the cases had fever

and the average persistence time from onset to admission was 3.64 days;the general symptoms were common

including cough

hypodynamia

muscle ache

chest distress

and nausea.Early anti-virus and 3-7days of low-dose glucocorticoids therapies

and immunity enhancement and antibacterial therapies in later period gained success in some cases.The intimate cooperation of multi-department staff and refined therapy were very important.Conclusion:The virulence and mortality of A H1N1 influenza is similar to seasonal influenza.As to critical A H1N1 influenza cases

we should afford inchoate anti-virus

and antibacterial therapy and subtle intensive therapy in later period to improve survival.

关键词

甲型H1N1流感危重症奥司他韦甲型H1N1流感抗体血浆糖皮质激素丙种球蛋白机械通气

Keywords

critical A H1N1 influenzaoseltamivirblood plasma with A H1N1 influenza virus antibodyglucocorticoidimmunoglobulinmechanical ventilation

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