The study of gastric motility in sub-types of gastroesophageal reflux disease

WU Qiao-yan1; ZHOU Xu-chun1; LIU Mao-qiang1; LI Zhang-yong2; LIU Chun-lun1

doi:10.13406/j.cnki.cyxb.2011.06.015

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The study of gastric motility in sub-types of gastroesophageal reflux disease

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- The study of gastric motility in sub-types of gastroesophageal reflux disease
- Journal of Chongqing Medical University Vol. 36, Issue 6, Pages: 738-740(2011)
- 作者机构：
  
  1. 重庆医科大学附属第一医院消化内科
  2. 重庆邮电大学生物信息学院
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2011.06.015
  CLC： R571
- Published：2011，
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[1]吴巧艳,周旭春,刘茂强,李章勇,刘纯伦.不同亚型胃食管反流病患者胃动力检测的研究[J].重庆医科大学学报,2011,36(06):738-740.

WU Qiao-yan1, ZHOU Xu-chun1, LIU Mao-qiang1, et al. The study of gastric motility in sub-types of gastroesophageal reflux disease. [J]. Journal of Chongqing Medical University 36(6):738-740(2011)
[1]吴巧艳,周旭春,刘茂强,李章勇,刘纯伦.不同亚型胃食管反流病患者胃动力检测的研究[J].重庆医科大学学报,2011,36(06):738-740. DOI： 10.13406/j.cnki.cyxb.2011.06.015.

WU Qiao-yan1, ZHOU Xu-chun1, LIU Mao-qiang1, et al. The study of gastric motility in sub-types of gastroesophageal reflux disease. [J]. Journal of Chongqing Medical University 36(6):738-740(2011) DOI： 10.13406/j.cnki.cyxb.2011.06.015.

摘要

目的:采用生物阻抗胃动力检测系统和评价方法研究不同亚型胃食管反流病（Gastroesophageal reflux disease

GERD）患者胃动力情况。方法:选取103例GERD患者

行GERD的反流症状（Gastroeso phageal reflux disease

GerdQ）评分

并通过胃动力检测系统提取胃电和胃阻抗信号

与对照组相比较

并进行不同亚型GERD之间胃电和胃阻抗信号的组间比较。结果:反流性食管炎（Reflux esophagitis

RE）组GerdQ评分为（12.52±8.49）

非糜烂性反流病（Non-erosive reflux disease

NERD）组GerdQ评分为（15.14±8.01）

Barrett食管（Barretts’esophagus

BE）组GerdQ评分为（7.20±7.10）。与对照组比较

不同亚型GERD的胃电和胃阻抗异常明显增加

差异有统计学意义（P<0.05）。RE组胃电和胃阻抗异常较NERD组、BE组更明显

NERD组胃阻抗中频百分比低于BE组

而低频百分比高于BE组（P<0.05）。NERD反流症状评分与胃阻抗异常相关r（s=-0.032）。结论:GERD各亚型均存在不同程度的胃动力异常

以RE组最明显。在NERD中反流症状与胃动力异常有关。

Abstract

Objective:To investigate the situation of gastric motility by using bio-electrical impedance method among the subtypes of gastroesophageal reflux disease(GERD).Methods:One hundred and three GERD outpatients were assigned to receive the GerdQ grade;impedance signal and electrical signal were detected and compared with the control group.Then the impedance signal and electrical signal among subtypes of GERD were compared.Results:The GerdQ score in RE was 12.52±8.49;NERD was 15.14±8.01;and BE was 7.20±7.10.The proportion of abnormal gastric motility in subtypes of GERD was higher than that in the control group.The proportion of abnormal gastric motility in RE was higher than in NERD and BE.The percentage of NERD was lower than the percentage of BE in median frequency of gastric impedance

but higher than that of BE in low frequency(P<0.05).There was negative correlation bewteen GerdQ and gastric impedance low frequency in NERD(rs=-0.032).Conclusion:There is abnormal gastric motility in subtype GERD

especially in RE.The reflux symptoms score has correlation with gastric motility in NERD.

关键词

胃食管反流病胃电胃阻抗

Keywords

gastroesophageal reflux diseaseelectrogastrogramgastric impedance

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