HUANG Chun, YE Lin, XIANG Xiao-yong. Noninvasive positive pressure ventilation in the treatment of cardiothoracic patients with acute respiratory failure. [J]. Journal of Chongqing Medical University 36(6):744-747(2011)
HUANG Chun, YE Lin, XIANG Xiao-yong. Noninvasive positive pressure ventilation in the treatment of cardiothoracic patients with acute respiratory failure. [J]. Journal of Chongqing Medical University 36(6):744-747(2011) DOI: 10.13406/j.cnki.cyxb.2011.06.012.
Noninvasive positive pressure ventilation in the treatment of cardiothoracic patients with acute respiratory failure
Objective:To compare the clinical effects of noninvasive positive pressure ventilation(NPPV) and invasive positive pressure ventilation(IPPV) in patients with acute respiratory failure(ARF)
and evaluate the effect of NPPV on the treatment of ARF.Methods:32 patients with Light
medium type ARF caused by various disorders were divided randomly into NPPV group(16 cases) and IPPV group(16 cases).Patients in two groups were treated by NPPV through a face mask or IPPV with endotracheal intubation respectively while medical therapy.Arterial blood gases were analyzed
and the rate of complication and outcome were observed.Results:In NPPV group
5 patients were transformed into IPPV for worsening condition and arterial blood gases.mortality rate in NPPV group(18.75%)was lower compared to IPPV group(25%)(P<0.05).After 6 hours of ventilatory support therapy
artery blood gas of cured patients of two groups improved significantly and similarly.Duration of mechanical ventilation and hospital stay in patients receiving NPPV were significantly shorter than those in patients receiving IPPV(P<0.05).Rate of complication in NPPV group was lower than that in IPPV group(P<0.05).Conclusion:Clin ical efficacy of NPPV were similar to IPPV in selected patients with ARF.Use of NPPV in patients with ARF might reduce duration of mechanical ventilation and hospital stay
and decrease rate of complication.NPPV might be the first choice for ventilatory support in selected patients with ARF.
Clinical evaluation of noninvasive positive pressure ventilation in multiple injury patients with acute lung injury and acute respiratory distress syndrome
Related Author
Gu Man-ping
et al
范晶
Related Institution
Department of Central Intensive Care Unit,the First Affiliated Hospital,Chongqing Medical University