Clinical analysis of 268 patients of severe HFMD infection

BAI Ke; et al

doi:10.13406/j.cnki.cyxb.2011.04.031

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Clinical analysis of 268 patients of severe HFMD infection

更新时间：2024-01-17

- Clinical analysis of 268 patients of severe HFMD infection
- Journal of Chongqing Medical University Vol. 36, Issue 4, Pages: 498-500(2011)
- 作者机构：
  
  1. 重庆医科大学附属儿童医院PICU
  2. 重庆市荣昌县昌元镇卫生院内科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2011.04.031
  CLC： R725.1
- Published：2011，
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[1]白科,刘成军,林晓娟,许峰.268例重症手足口病患儿临床分析[J].重庆医科大学学报,2011,36(04):498-500.

BAI Ke, et al. Clinical analysis of 268 patients of severe HFMD infection. [J]. Journal of Chongqing Medical University 36(4):498-500(2011)
[1]白科,刘成军,林晓娟,许峰.268例重症手足口病患儿临床分析[J].重庆医科大学学报,2011,36(04):498-500. DOI： 10.13406/j.cnki.cyxb.2011.04.031.

BAI Ke, et al. Clinical analysis of 268 patients of severe HFMD infection. [J]. Journal of Chongqing Medical University 36(4):498-500(2011) DOI： 10.13406/j.cnki.cyxb.2011.04.031.

摘要

目的:探讨重症手足口病（Hand

foot and mouth disease

HFMD）的诊治经验。方法:依据临床表现及并发症将268例重症HFMD患儿分为重症及危重症两组

对其临床表现、病情动态变化、辅助检查、治疗及转归进行回顾性分析。结果:268例重症HFMD患儿

男159例（59.3%）

女109例（40.7%）;年龄5个月

0岁

3岁者231例（86.2%）

平均年龄2.9岁。Ⅰ重症组

并发症以神经系统症状为主要表现者232例（86.6%）

均存活

肠道病毒71型（Enterovirus 71

EV71）阳性135（58.2%）例;Ⅱ危重症组

并发神经、循环、呼吸等系统多器官损害者36例（13.4%）

24例（8.95%）死亡

其中20例入院24 h内死亡

EV71阳性28例。结论:HFMD重症危重型病情进展快

死亡率高

早期发现正确治疗是抢救成功的关键。

Abstract

Objective:To investigate the diagnosis and treatment of severe hand

foot and mouth disease(Hand

Foot and Mouth Disease

HFMD).Methods:According to clinical manifestations and complications

268 HFMD patients were divided into severe case group and critical case group

and then the clinical manifestations

illness dynamic changes

auxiliary examinations

treatments and prognoses were retrospectively analyzed.Results:Among the 268 severe HFMD infection patients

159 were male patients(59.3%)

and 109 were female patients(40.7%).The age of patient was from 5 months to 10 years old.Among them

younger than 3 years old patients were 231 cases(86.2%)with an average age of 2.9 years old.In severe case group

complications in neurological system as main behavior were in 232 patients(86.6%)

who were alive

and EV71 positive was in 135(58.2%)patients;In critical case group

multiple organ damages in nervous

circulatory

and respiratory system were in 36 cases(13.4%)

and 24 cases(8.95%)died

including 20 cases died within 24 h hospitalization

and EV71 positive was in 28 cases.Conclusion:HFMD severe critical type progresses fast

and with high mortality rate.An early discovery and correct treatment is the key to successful rescue.

关键词

手足口病重症危重症肠道病毒EV71早期诊断

Keywords

handfoot and mouth disease(HFMD)severe casecritical caseintestinal virus EV71early diagnosis

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