Effect of medified electroconvulsive therapy on the cognition of patients with major depression disorder

LOU Dan-dan; et al

doi:10.13406/j.cnki.cyxb.2011.03.028

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Effect of medified electroconvulsive therapy on the cognition of patients with major depression disorder

更新时间：2024-01-17

- Effect of medified electroconvulsive therapy on the cognition of patients with major depression disorder
- Journal of Chongqing Medical University Vol. 36, Issue 3, Pages: 342-343(2011)
- 作者机构：
  
  重庆医科大学附属第一医院心理卫生中心
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2011.03.028
  CLC： R749.4
- Published：2011，
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[1]楼丹丹,况利,甘窈.MECT对严重抑郁患者认知功能的影响[J].重庆医科大学学报,2011,36(03):342-343.

LOU Dan-dan, et al. Effect of medified electroconvulsive therapy on the cognition of patients with major depression disorder. [J]. Journal of Chongqing Medical University 36(3):342-343(2011)
[1]楼丹丹,况利,甘窈.MECT对严重抑郁患者认知功能的影响[J].重庆医科大学学报,2011,36(03):342-343. DOI： 10.13406/j.cnki.cyxb.2011.03.028.

LOU Dan-dan, et al. Effect of medified electroconvulsive therapy on the cognition of patients with major depression disorder. [J]. Journal of Chongqing Medical University 36(3):342-343(2011) DOI： 10.13406/j.cnki.cyxb.2011.03.028.

摘要

目的:评定无抽搐电休克治疗对严重抑郁患者认知功能产生的影响。为临床无抽搐电休克治疗提供理论依据。方法:符合中国精神障碍分类与诊断标准第3版的抑郁症标准

汉密尔顿抑郁量表（Hamilton depression scale

HAMD）17项总分≥24分的严重抑郁症患者进行了至少6次双侧电极无抽搐电休克治疗

分别于治疗前、第1次治疗后、第6-8次治疗后进行汉密尔顿抑郁量表（HAMD）及韦氏记忆量表（Wechsler memoryscale

WMS）评定。结果:无抽搐电休克治疗严重抑郁症后临床症状明显好转（P<0.01）

但对记忆有一定的影响

这种影响于患者接受第6次至第8次治疗时逐渐恢复。结论:无抽搐电休克治疗对严重抑郁症患者临床症状有明显的改善

且对患者记忆的影响是可逆的。

Abstract

Objective: To estimate the influence of modified electroconvulsive therapy(MECT) on the cognition of patients with major depression.Methods: Patients metting CCMD-3 criteria for major depression

whose scores of HAMD 17-item were above 24

were treated with bilateral

brief pulse

square-wave stimulus

dose titration MECT.Before and after the 1st and 6~8th course of treatment

Hamilton depression scale and Wechsler memory scale were tested.Results:There was significant amelioration of clinical symptoms after MECT(P <0.01)

but it had negative impact on memory

which would last till the 6~8th course of treatment.Conclusion: MECT may improve the symptoms of patients with severe depression and irreversibly influnce the memory.

关键词

无抽搐电抽搐治疗严重抑郁症认知

Keywords

modified electroconvulsive therapy(MECT)major depressioncognition

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