Analysis of cardiac reserve in children with ASD before and after intervention

HUO Jun-ming; et al

doi:10.13406/j.cnki.cyxb.2011.02.025

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Analysis of cardiac reserve in children with ASD before and after intervention

更新时间：2024-01-17

- Analysis of cardiac reserve in children with ASD before and after intervention
- Journal of Chongqing Medical University Vol. 36, Issue 2, Pages: 203-205(2011)
- 作者机构：
  
  1. 重庆医科大学附属儿童医院心脏中心
  2. 重庆大学生物工程学院生物医学工程系
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2011.02.025
  CLC： R725.4
- Published：2011，
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[1]霍俊明,易岂建,肖守中,谢梅兰,肖子夫.房间隔缺损患儿介入封堵术前后心脏储备功能的评估[J].重庆医科大学学报,2011,36(02):203-205.

HUO Jun-ming, et al. Analysis of cardiac reserve in children with ASD before and after intervention. [J]. Journal of Chongqing Medical University 36(2):203-205(2011)
[1]霍俊明,易岂建,肖守中,谢梅兰,肖子夫.房间隔缺损患儿介入封堵术前后心脏储备功能的评估[J].重庆医科大学学报,2011,36(02):203-205. DOI： 10.13406/j.cnki.cyxb.2011.02.025.

HUO Jun-ming, et al. Analysis of cardiac reserve in children with ASD before and after intervention. [J]. Journal of Chongqing Medical University 36(2):203-205(2011) DOI： 10.13406/j.cnki.cyxb.2011.02.025.

摘要

目的:用基于心力-心音关系的方法和指标对房间隔缺损（Atrial septal defect

ASD）患儿介入术前后心脏储备功能的改变进行初步研究。方法:把实验对象分为单纯ASD患儿（n=20）组

ASD伴肺动脉高压（Pulmonary hypertension

PAH）患儿组（n=20）和对照组（n=20）3组

采用运动心力监测仪记录前2组介入前

介入后1 d

介入后6个月的静息状态下心音图

用同样方法记录对照组心音图

用心脏储备软件测量第一心音幅值（S1）、第二心音幅值（S2）、舒张期（D）和收缩期（S）时限

比较第一心音与第二心音幅值之比（S1/S2）

舒张期与收缩期的时限之比（D/S）在各组间的差异。结果:与对照组相比

介入前ASD患儿S1/S2比值和D/S比值均降低

其中ASD伴PAH组降低更明显;S1/S2比值、D/S比值介入后升高

介入后6个月升高更明显。结论:ASD患儿介入前心脏储备功能降低

介入后心脏储备功能增加。

Abstract

Objective: To investigate cardiac reserve by using a method based on the relation between cardiac contractility and heart sound in children with ASD before and after intervention.Methods: Children with ASD(n=20)

and ASD with pulmonary hypertension(n = 20)

and normal control(n= 20) were enrolled in this study.The phonocardiograms were recorded for each control subject

each patient with ASD and ASD with pulmonary hypertension at rest before the intervention

one day after the intervention

and 6 months after the intervention by using a cardiac contractility monitor.The first heart sound amplitude(S1)

the second heart sound amplitude(S2)

diastolic(D) and systolic(S) durations were measured with cardiac reserve software.The ratios of S1/S2 and D/S were analysed.Results: Compared with the control

the ratios of S1/S2 and D/S were lower in the ASD before intervention

which were the lowest in the ASD with pulmonary hypertension.The ratios of S1/S2 and D/S were increased after intervention

and more significantly increased 6 months after intervention.Conclusion: The cardiac reserve in children with ASD decreases before intervention

and increases after intervention.

关键词

ASD儿童S1/S2舒张期/收缩期时限比值心脏储备

Keywords

ASDchildrenS1/S2D/Scardiac reserve

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