Objective:To explore the importance of noninvasive positive pressure ventilation(NIPPV) in treating patients suffered from multiple injury accompanied with acute lung injury(ALI)/acute respiratory distress syndrome(ARDS)

and summarize the clinical usage of bi-level airway pressure ventilation mode in the treatment.Methods:The 75 cases with multiple injury complicated with ALI/ARDS were analyzed retrospectively and the following two groups were obtained:the positive pressure ventilation group

in abbreviation NIPPV

and the invasive mechanical ventilation group

in abbreviation IMV.The changes of arterial blood gas individually before and after 2 h treatment and the duration of using ventilation were compared between the two groups.Results:40 cases were enrolled into NIPPV group

and 35 cases belong to IMV group.The arterial partial pressure of oxygen(PaO2) and arterial oxygen saturation(SaO2) had significantly improved after 2 h NIPPV or IMV treatment(both P <0.000 1).5 patients changed to IMV after 3～5 days NIPPV(average=4.2 d)according to their conditions.4 patients who needed general anesthesia operations were given IMV for 20～36 h

then were changed to NIPPV.Duration of using NIPPV were 3～18 d(average=(8±5.5) d)

and duration of using IMV were 5～20 d(average=(9±5.5) d).The changes of arterial blood gas showed no significant difference between NIPPV and IMV at the statistic level of P>0.05.No patient died in two groups.Conclusion:The use of bi-level airway pressure ventilation on NIPPV mode in early stage of multiple injury patients with ALI/ARDS not only has same effect as using IMV

but also can reduce complications and improve patients’ comfortableness.