Study of the methods of extracting and analyzing characteristic signal of eyeblink response in conscious guinea pigs

WU Guang-yan; et al

doi:10.13406/j.cnki.cyxb.2010.12.002

您当前的位置：

首页 >

文章列表页 >

Study of the methods of extracting and analyzing characteristic signal of eyeblink response in conscious guinea pigs

更新时间：2024-01-17

- Study of the methods of extracting and analyzing characteristic signal of eyeblink response in conscious guinea pigs
- Journal of Chongqing Medical University Vol. 35, Issue 12, Pages: 1828-1831(2010)
- 作者机构：
  
  1. 第三军医大学学员旅三队
  2. 重庆大学通讯学院实验中心
  3. 第三军医大学基础部教学实验中心
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2010.12.002
  CLC： R-332
- Published：2010，
扫描看全文
[1]吴广延,范郑丽,甘平,柴东,万子兵,赵红梅,隋建峰.清醒豚鼠眨眼反射信号的提取与分析方法的研究[J].重庆医科大学学报,2010,35(12):1828-1831.

WU Guang-yan, et al. Study of the methods of extracting and analyzing characteristic signal of eyeblink response in conscious guinea pigs. [J]. Journal of Chongqing Medical University 35(12):1828-1831(2010)
[1]吴广延,范郑丽,甘平,柴东,万子兵,赵红梅,隋建峰.清醒豚鼠眨眼反射信号的提取与分析方法的研究[J].重庆医科大学学报,2010,35(12):1828-1831. DOI： 10.13406/j.cnki.cyxb.2010.12.002.

WU Guang-yan, et al. Study of the methods of extracting and analyzing characteristic signal of eyeblink response in conscious guinea pigs. [J]. Journal of Chongqing Medical University 35(12):1828-1831(2010) DOI： 10.13406/j.cnki.cyxb.2010.12.002.

摘要

目的:介绍一种从清醒豚鼠眨眼反射记录中有效地提取并分析其惊吓性眨眼反射（Eyeblink startle response

EBSR）、条件性眨眼反射以及非条件眨眼反射（Eyeblink unconditionel response

EBUR）波形的方法。方法:采用正弦波纯音和束状医用氧气流分别作为条件刺激和非条件刺激先后作用于豚鼠

训练豚鼠建立眨眼条件反射（Eyeblink conditioned response

EBCR）

在此过程中利用高分辨率、低扭矩的肌肉张力换能器测量眨眼活动

并通过基线计算与文件取舍等步骤分析这些测量数据。结果:该方法可以快速准确地对眨眼反射记录进行有效提取和分析

并与其它方法的相关报道一致。结论:该眨眼反射测量方法操作和分析过程简单

结果准确

可用于研究小型啮齿类动物EBCR训练中眨眼活动的拓扑学参数变化。

Abstract

Objective:To introduce a method which can effectually extract records of eyeblink response and analyze wave shape of eyeblink startle response

eyeblink conditioned response and eyeblink unconditioned response in conscious guinea pigs.Methods:Sine wave sounds and medical oxygen flow bundle were used successively as conditioned stimulus and unconditioned stimulus to train guinea pigs

to establish eyeblink conditioned response.High-resolution and low-torque muscle tension transducers were used to measure eyeblink activity in the process

and through the baseline calculation

document selection and other steps

these measurements were analyzed.Results:The method could rapidly and accurately extract and analyze records of eyeblink response

and was consistent with other reported.Conclusion:The eyeblink response measurement method and analyzing process are simple and the result is accurate.The method can be used to study the change of eyeblink activity topology parameter in training process of eyeblink conditioned response in small rodents.

关键词

豚鼠眨眼反射张力换能器信号基线

Keywords

guinea pigEyeblink responseTension transducersSingleBaseline

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Expression and forensic significance of interleukin-4，interleukin-13 and immunoglobulin E in guinea pigs died of anaphylactic shock

Related Author

LIU Yong

CHEN Xiaoqian

LI Hang

YU Jian

Related Institution

Department of Forensic Medicine，Zunyi Medical College

Department of Pathology， People’s Hospital of Renhuai City in Guizhou Province

⁰