RAN Wen-hua, et al. Clinical reasearch of limited stage small cell lung cancer treated by Chinese medcine after chemoradiotherapy. [J]. Journal of Chongqing Medical University 35(11):1756-1758(2010)
RAN Wen-hua, et al. Clinical reasearch of limited stage small cell lung cancer treated by Chinese medcine after chemoradiotherapy. [J]. Journal of Chongqing Medical University 35(11):1756-1758(2010) DOI: 10.13406/j.cnki.cyxb.2010.11.042.
Clinical reasearch of limited stage small cell lung cancer treated by Chinese medcine after chemoradiotherapy
Objective:To investigate whether Chinese traditional medcine improve survival rate of limited stage small cell lung cancer(LS-SCLC) patients after conventional chemoradiotherapy.Method: Seventy patients with LS-SCLC treated without surgery were randomized into two groups.The control group 35 examples treated by chemoradiotherapy
35 cases of patients in the research group treated based on chemoradiotherapy plus Chinese Medicine
XIDAN soup was given by mouth during strengthen phase
consolidation phase and maintenance phase.Result:The overall 1-
2-
3-
5-year survival rates of LS-SCLC patients in the control group and experimental group were 74.3%
31.4%
14.3%
11.4% and 77.1%
40.0%
28.6%
22.9% respectively
and the median survival for two groups were 16.1 months and 22.3 months respectively.The difference of survival rate at years 2
3
5 in two groups had statistically significance(P<0.05).But the difference of gastrointestinal reactions and myelosuppression atⅠ
Ⅱ levels during strengthen phase in two groups had no statistically significance(P>0.05).Conclusion:Chinese medcine treatment after conventional chemoradiotherapy can improve the survival rate and lengthen the survival time of LS-SCLC patients without increasing toxic side effects.
关键词
局限期小细胞肺癌放化疗后中药维持治疗中西医结合治疗
Keywords
Limited stage small cell lung cancerPost-chemora-diotherapyFollow up treatment by Chinaes medicinecombination of Chinese and Western medicine treatment