Epidemiological data analysis of newly diagnosed childhood leukemia in Chongqing between 2000 and 2009

ZHU Mei-jun; et al

doi:10.13406/j.cnki.cyxb.2010.11.041

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Epidemiological data analysis of newly diagnosed childhood leukemia in Chongqing between 2000 and 2009

更新时间：2024-01-17

- Epidemiological data analysis of newly diagnosed childhood leukemia in Chongqing between 2000 and 2009
- Journal of Chongqing Medical University Vol. 35, Issue 11, Pages: 1742-1745(2010)
- 作者机构：
  
  重庆医科大学附属儿童医院血液肿瘤科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2010.11.041
  CLC： R733.7
- Published：2010，
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[1]朱美君,徐酉华,胡艳妮.重庆地区2000～2009年儿童白血病流行病学回顾性分析[J].重庆医科大学学报,2010,35(11):1742-1745.

ZHU Mei-jun, et al. Epidemiological data analysis of newly diagnosed childhood leukemia in Chongqing between 2000 and 2009. [J]. Journal of Chongqing Medical University 35(11):1742-1745(2010)
[1]朱美君,徐酉华,胡艳妮.重庆地区2000～2009年儿童白血病流行病学回顾性分析[J].重庆医科大学学报,2010,35(11):1742-1745. DOI： 10.13406/j.cnki.cyxb.2010.11.041.

ZHU Mei-jun, et al. Epidemiological data analysis of newly diagnosed childhood leukemia in Chongqing between 2000 and 2009. [J]. Journal of Chongqing Medical University 35(11):1742-1745(2010) DOI： 10.13406/j.cnki.cyxb.2010.11.041.

摘要

目的:分析10年间重庆医科大学附属儿童医院收治的915例白血病患儿的流行病学资料

探讨重庆地区儿童白血病分布特征及规律。方法:对2000年1月至2009年12月我院收治的915例儿童白血病病例的流行病学资料进行回顾性分析。结果:10年间儿童白血病初发病例共915例

平均年增长速度19.6%。型别最多为急性淋巴细胞白血病（Acute lymphoblastic leukemia

ALL）

ALL免疫表型中B系表达为主

初诊白血病核型异常率为47.59%。男性发病率高于女性。10岁以下白血病患儿737例占80.55%

ALL患儿以1～4岁组最多。结论:我院儿童白血病初发病例数呈逐年上升趋势

可能与环境污染加重及就诊病例数增加有关。重庆地区特有的儿童白血病流行病学特征

提示遗传及环境因素在白血病起源中作用

从而导致预后的差别。

Abstract

Objective:To investigate the epidemiological characteristics of newly diagnosed childhood leukemia in Children’s Hospital of Chongqing Medical University between 2000 and 2009

and to understand the features of childhood leukemia in the region of Chongqing

so as to provide references for prevention of childhood leukemia.Methods:The records of 915 children with leukemia who were initially diagnosed at Children’s Hospital of Chongqing Medical University from January 2000 to December 2009 were retrospectively studied.Results:The number of cases increased from 26 up to 156 in this decade

with annual increase of 19.6%.Of the 915 patients

71.48% were diagnosed as Acute lymphoblastic leukemia(ALL)

among whom

382 children were classified as B-cell ALL.47.59% patients had clonal abnormalities.The ratio of males to females was 1.63:1.Most of the patients were younger than 10 years(80.55%).ALL was most common in 1～4 years age group.Conclusions:The newly diagnosed childhood leukemia has continuously upward trend in Children’s Hospital of Chongqing Medical University.There are differences in the epidemiological characteristics of childhood leukemia between Chongqing and other regions

which suggests that there might be differences in the pathogenesis of childhood leukemia in different ethic origins and different environmental exposures.

关键词

儿童白血病流行病学资料

Keywords

childhoodleukemiaEpidemiological characteristics

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重庆医科大学第一医院内科血液组重庆医科大学检验科

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