Objective:To study the clinical treatment effects of thoracolumbar fractures with posterior pedicle screw fixation supplemented with nano-hydroxyapatite/polyamide 66(n-HA/PA66) composite grafted into vertebra by transpedicle of vertebral arch.Methods:Thirty-six patients with thoracolumbar fractures were treated with the posterior pedicle screw fixation supplemented with n-HA/PA66 composite grafted into vertebra by transpedicle of vertebral arch.The anterior height of the injured vertebrae was measured for analysis of the recovery degree of vertebrae height.Furthermore

the conditions of bone grafting fusion were also observed.Results:Thirty-six cases were followed up for average 29.3 months.The vertebral height and physiological curvature were recovered satisfactorily.The bone fusions of vertebral bone grafted were good and the internal fixations were firm.Comparing the anterior height of the injured vertebrae a week after operation and at the end of follow-up with the normal value respectively

the difference was not significant(P>0.05).Comparing the anterior height of the injured vertebrae after operation with preoperative value

the difference was significant(P<0.05).Conclusion :The present study demonstrates that pedicle screw fixation combined with anterior column reconstruction with n-HA/PA66 composite by transpedicle of vertebral arch can effectively reconstruct the stability of spinal column.The treatment is helpful to reduce the vertebral "eggshell" effect and prevent the occurrence of vertebral collapse.