The importance of Prethrombotic state detection in the early warning for thrombosis in PICC

ZHANG Xiu-li; et al

doi:10.13406/j.cnki.cyxb.2010.10.008

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The importance of Prethrombotic state detection in the early warning for thrombosis in PICC

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- The importance of Prethrombotic state detection in the early warning for thrombosis in PICC
- Journal of Chongqing Medical University Vol. 35, Issue 10, Pages: 1589-1591(2010)
- 作者机构：
  
  重庆医科大学附属第一医院呼吸内科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2010.10.008
  CLC： R446.11
- Published：2010，
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[1]张秀丽,罗艳,杨相梅.血栓前状态的检测对PICC血栓形成的预警意义[J].重庆医科大学学报,2010,35(10):1589-1591.

ZHANG Xiu-li, et al. The importance of Prethrombotic state detection in the early warning for thrombosis in PICC. [J]. Journal of Chongqing Medical University 35(10):1589-1591(2010)
[1]张秀丽,罗艳,杨相梅.血栓前状态的检测对PICC血栓形成的预警意义[J].重庆医科大学学报,2010,35(10):1589-1591. DOI： 10.13406/j.cnki.cyxb.2010.10.008.

ZHANG Xiu-li, et al. The importance of Prethrombotic state detection in the early warning for thrombosis in PICC. [J]. Journal of Chongqing Medical University 35(10):1589-1591(2010) DOI： 10.13406/j.cnki.cyxb.2010.10.008.

摘要

目的:探讨血栓前状态的检测对外周静脉置入中心静脉导管（Peripherally inserted central catheter

PICC）血栓形成的预警意义。方法:通过随机抽取我科30例PICC置管患者

以2009年6月19日

010年2月22日的临床检验资料进行统计分析。通过对PICC置管前0

d（T0）、置管后2

d（T1）、置管后4

1 d（T2）与血栓形成相关量化指标凝血酶原时间（Prothrombin time

PT）、凝血活酶时间（Activated partial thromboplsatin time

APTT）、凝血酶时间（Thrombin time

TT）、纤维蛋白原量（Fibrinogen

Fbg）、纤维蛋白降解产物（Fibrinogen degradation products

FDP）及D-二聚体的动态检测

对比T0与T1、T0与T2、T1与T2

观察各时间段各项指标的变化。结果:T0与T1比较

2组PLT值有显著差异（P

0.05）

而PT、APTT、TT、Fbg、FDP及D-二聚体则统计学差异不明显;T0与T2比较

PT、APTT、TT、PLT、Fbg、FDP及D-二聚体统计学差异亦不明显;T1与T2比较

PT、APTT、TT、PLT、Fbg、FDP及D-二聚体统计学差异同样不明显。结论:只有PLT在T0与T1时间段具有显著差异

提示置管后2

d检测外周血血小板（Plateled

PLT）在PICC血栓形成前具有预警意义。

Abstract

Objective:Tostudythe earlywarningmeaningofprethrombotic state test before thrombosis caused byPICC. Methods:Clinical data of 30 patients selected randomly in our department during 2009.6.19~2010.2.22 was analyzed retrospectively. All the parameters brought into our study included PT

APTT

PLT

Fbg

FDP and D-dimer. Every parameter was dynamically detected 3 times

0~1 days before (T0)

2~3 days after (T1)

4~11 days after (T2) PICC inserted. Three values of each parameter were compared in pairwise comparison. Results:The difference of PLT between T0 and T1 was significant (P<0.05). There was no significant difference in PT

APTT

Fbg

FDP and D-dimer between T1 and T0 (P>0.05). Between T0 and T2

T1 and T2

there was no significant difference in all the 7 parameters(P>0.05). Conclusion:As the significant difference in PLT between T0 and T1

PLT test before and 2~3 days after PICC inserted may have great meaning of early warning thrombosis.

关键词

血栓前状态PICC预警

Keywords

prethrombotic statePeripherallyinserted central catheterEarlywarningmeaning

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Related Author

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Related Institution

Department of Respiratory Medicine，The First Affiliated Hospital of Chongqing Medical University

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