The effects of statins in recurrence cerebral infarction

GAO Juan; et al

doi:10.13406/j.cnki.cyxb.2010.08.025

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The effects of statins in recurrence cerebral infarction

更新时间：2024-01-17

- The effects of statins in recurrence cerebral infarction
- Journal of Chongqing Medical University Vol. 35, Issue 8, Pages: 1262-1263(2010)
- 作者机构：
  
  1. 河北大学附属医院神经内科
  2. 承德医学院附属医院神经内科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2010.08.025
  CLC： R743.3
- Published：2010，
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[1]高娟,孙雅菲.他汀类药物在预防脑梗死复发中的作用[J].重庆医科大学学报,2010,35(08):1262-1263.

GAO Juan, et al. The effects of statins in recurrence cerebral infarction. [J]. Journal of Chongqing Medical University 35(8):1262-1263(2010)
[1]高娟,孙雅菲.他汀类药物在预防脑梗死复发中的作用[J].重庆医科大学学报,2010,35(08):1262-1263. DOI： 10.13406/j.cnki.cyxb.2010.08.025.

GAO Juan, et al. The effects of statins in recurrence cerebral infarction. [J]. Journal of Chongqing Medical University 35(8):1262-1263(2010) DOI： 10.13406/j.cnki.cyxb.2010.08.025.

摘要

目的:探讨阿托伐他汀在预防脑梗死复发中的作用。方法:将579例脑梗死患者分成阿司匹林治疗组与阿托伐他汀治疗组

阿托伐他汀治疗组在阿司匹林治疗的基础上加用阿托伐他汀20mg

每晚1次

随访观察6～36月

观察脑梗死复发情况。结果:根据随机分组

治疗前两组一般情况和脑梗死复发危险因素无差异（P>0.05）

286例阿司匹林组患者在随访期复发57例（19.9%）

而阿托伐他汀组仅有28例（9.6%）复发

2组在统计学上有差异（P<0.05）。结论:阿司匹林治疗的基础上加用阿托伐他汀治疗能明显降低脑梗死复发率。

Abstract

Objective:To explore the effects of statins in recurrence cerebral infarction.Methods:579 patients with cerebral infarction were randomly divided into aspirin group(286 cases)and the atorvastatin group(293 cases)

and the patients in both groups were given aspirin as routine treatment

however

the patients in atorvastatin group were Also administered atorvastatin 20 mg every night.The duration of follow-up was 6 to 36months.Results:57 patients suffered new cerebral infarction during follow-up period in aspirin group(19.9%); On the other hand

28 patients suffered new cerebral Infarction during follow-up period in the atorvastatin group(9.6%).There was asignificant differentce between the two groups(P<0.05).Conclusion:Atorvastatin can decrease the recurrence rate of cerebral infarction on the basis of aspirin treatment.

关键词

阿托伐他汀脑梗死预后

Keywords

Atorvastatincerebral infarctionprognosis

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