Objective:To explore the management ofupper urinarytract infections caused pseudomonas aeruginosa after operation ofupper urinary tract obstruction.Methods:A total of 30 cases with upper urinary tract obstruction

which had undergone pyeloureteroplasty or lithonephrotomy and been placed double-J tubes intraoperatively and been infected by pseudomonas aeruginosa

were treated from March 2004 to May 2009.They had undergone retrograde urography before operation

double-J tube were retained for 2 weeks or more postoperatively;PA were isolated by urine culture and colony count>1×105/ml。These cases were assigned to A or B group randomly.The management of A group:double-J tubes were placed and retained for 2 weeks again

and used susceptible antibiotics for 2 weeks→ discontinued drugs for 1 week→urine cultured

PA(+)→used susceptible antibiotics for 2 weeks→discontinued drugs for 1 week→urine cultured

PA(+)→used susceptible antibiotics for 2 weeks;the management of B group:double-J tube(sCook

F6

America)were placed again

and used susceptible antibiotics for 2 weeks→discontinued drugs for 1 week→urine cultured

PA(+)→used susceptible antibiotics for 2 weeks

until the infection was cured

the double-J tube was removed after the infection was cured.Results:A group:double-J tubes were retained for 2 weeks additionally;4 patients were cured during the first two-week

2 patients were cured during the second two-week

the cure rate was 40%after two courses

one was cured during the third two-week

the cure rate was 46.7%after three courses.B group:double-J tubes was retained for 4～12 weeks(mean 8 weeks)additionally

3 patients were cured during the first two-week

9 patients were cured during the second two-week

the cure rate was 80%after two courses

2 patients were cured during the third two-week

the cure rate was 93.3%after three courses.The cure rate ofBgroup was significantlyhigher than Agroup after twocourses and three courses

the difference was significan(tP<0.05). Conclusion:The therapeutic effect on upper urinary tract infectionts caused by pseudomonas aeruginosa after operation of upper urinary tract obstruction

ofBtreatment perscription—double-J tube(sCook

F6

America)was placed again and used susceptible antibiotics

the double-J tube was removed after the infection was cured—was significantly better than that of A treatment pescription—double-J tubes was placed and retained for 2 weeks again

and used susceptible antibiotics.The former was an effective method

it is worth tospread clinically.