Application of propofol target controlled infusion for bronchoalveolar lavage in critical patients be treated by mechanical ventilation

CHANG Wen-li

doi:10.13406/j.cnki.cyxb.2010.07.020

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Application of propofol target controlled infusion for bronchoalveolar lavage in critical patients be treated by mechanical ventilation

更新时间：2024-01-17

- Application of propofol target controlled infusion for bronchoalveolar lavage in critical patients be treated by mechanical ventilation
- Journal of Chongqing Medical University Vol. 35, Issue 7, Pages: 1119-1121(2010)
- 作者机构：
  
  四川省绵阳市中心医院麻醉科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2010.07.020
  CLC： R614
- Published：2010，
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[1]畅文丽.异丙酚靶控镇静在机械通气患者纤支镜肺泡灌洗中的临床研究[J].重庆医科大学学报,2010,35(07):1119-1121.

CHANG Wen-li. Application of propofol target controlled infusion for bronchoalveolar lavage in critical patients be treated by mechanical ventilation. [J]. Journal of Chongqing Medical University 35(7):1119-1121(2010)
[1]畅文丽.异丙酚靶控镇静在机械通气患者纤支镜肺泡灌洗中的临床研究[J].重庆医科大学学报,2010,35(07):1119-1121. DOI： 10.13406/j.cnki.cyxb.2010.07.020.

CHANG Wen-li. Application of propofol target controlled infusion for bronchoalveolar lavage in critical patients be treated by mechanical ventilation. [J]. Journal of Chongqing Medical University 35(7):1119-1121(2010) DOI： 10.13406/j.cnki.cyxb.2010.07.020.

摘要

目的:研究机械通气病人异丙酚靶控镇静下的纤维支气管镜肺泡灌洗（Bronchoalveolar lavage

BAL）术中、术后情况变化

探讨异丙酚靶控镇静在机械通气病人中的应用价值。方法:61例收住ICU的机械通气病人随机分为2组:异丙酚靶控组（A组）和地西泮复合咪达唑仑组（B组）

监测并记录患者术前10min至术后Ramsay≤Ⅱ级前（术后监测≥10min）全程持续监测心电波形、呼吸、SPO2、血压。记录BAL持续时间

术后至Ramsay≤Ⅱ级时间

以及手术30min后患者对BAL过程的术中表现和主观回忆。结果:A组术中心率和呼吸降低较B组明显、术后10minA组低于B组;A组术中躁动、恶心、呕吐、呛咳等不良反应发生率低于B组

BSF持续时间A组较B组短;A组苏醒较B组快;对手术痛苦回忆A组少于B组;异丙酚靶控诱导剂量时A组心率、呼吸和SBP均较B组下降。结论:异丙酚靶控镇静在ICU机械通气病人的BAL中能有效改善患者应激状态

减少躁动、恶心、呕吐等BAL相关副反应

术后苏醒快

没有痛苦记忆存留

是较好的ICU介入性操作的镇静方式。

Abstract

Objective:To investigate the effect of disoprofol target controlled infusion for bronchoalveolar lavage in critical patients be treated by mechanical ventilation.Methods:61 cases in ICU

who were treated by mechanical ventilation

were randomly divided into 2 groups:disoprofol group(A-group)and diazepam combined with midazolam group(B-group)

monitoring and recording electrocardiogram wave form

breathing

SPO2 and blood pressure from preoperative 10 minutes to postoperative before Ramsay≤Ⅱ.Recording the time of bronchoalveolar lavage and postoperative before Ramsay≤Ⅱ

also the Patients’performance and subjective memory in the process of BAL after operation in 30 min.Results:HR and Br of A-group were much lower than B-group after operation 10 min.The restlessness

nausea

vomiting

choke cough adverse reaction rate of A-group were less than B-group during the operation.The time of BAL in A-group was shorter than B-group.A-group of awakening is faster than B-group.Surgery and painful memories in A-group were less than B-group. When propofol target control induction dose

Br and SBP of A-group were much lower than B-group.Conclusion:Propofol target controlled infusion can effectively improve the stress state of patients who treated by mechanical ventilation

reducing the related side effects of BAL

such as restless

nausea and vomiting

awakening fast after operation

no pain memories

which is a good way of calm when the patients need interventional operation in Intensive Care Unit.

关键词

异丙酚靶控输注机械通气纤维支气管镜肺泡灌洗

Keywords

propofoltarget controlled infusionmechanical ventilationBronchoalveolar lavage

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Department of Anesthesiology, College of Clinical Medicine, Chongqing Medical University

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