XIAO Zhi-bo, et al. The study of radiology in the experiment of repairing bone defects with nano-hydroxyapatite and polyamide-66 composite. [J]. Journal of Chongqing Medical University 35(6):825-828(2010)
XIAO Zhi-bo, et al. The study of radiology in the experiment of repairing bone defects with nano-hydroxyapatite and polyamide-66 composite. [J]. Journal of Chongqing Medical University 35(6):825-828(2010) DOI: 10.13406/j.cnki.cyxb.2010.06.027.
The study of radiology in the experiment of repairing bone defects with nano-hydroxyapatite and polyamide-66 composite
Objective:Tostudy the MRI with X-ray in the ability of bony generation by the way of the experiment of repairing bone defects with n-HA/PA66. Methods:30 New Zealand rabbits were avalued whose condyle of tibia in one side was performed boring which was 3mm diameter and 5mm depth with n-HA/PA66 composite implanting. The specimens were taken respectively in different times:2nd 4th 6th 8th 12th week after surgery
and were examined by the methods of plain roentgenography、histology and magnetic resonance imaging. Results:(1)MRI and X-ray:From the 4th week
n-HA/PA66 composite had the poor defined border and the signal inter-material had become more variform
more obvious enhancement
at the same time in the X-ray
there were more and more bony generation(.2)The histology showed that a layer of interface membrane forming. From the 4th week
The interface membrane had been widest and the number of cells was increasing. Till the 12th week
there were some bone trabecula formed and the HA were separated into small islands
more osteoclasts appeared. Conclusion:The experimental results showthat the perfect radiology technique is useful to predict the bone transplantation. Furthermore it is easy to operate in clinical setting
and the n-HA/PA66 Composite has the attribute of good biocompatility and osteoconductibity
which can be manifested by plain roentgenography and magnetic resonance imaging.
关键词
骨移植MRI骨缺损纳米羟基磷灰石-聚酰胺66复合物
Keywords
Bone transplantMRIBone defectNano-hydroxyapatite and polyamide-66 composite