Observation on therapeutic effects of early stage mechanical ventilation in treating acute severe traumatic brain injury

LI Xing-hua; et al

doi:10.13406/j.cnki.cyxb.2010.04.043

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Observation on therapeutic effects of early stage mechanical ventilation in treating acute severe traumatic brain injury

更新时间：2024-01-17

- Observation on therapeutic effects of early stage mechanical ventilation in treating acute severe traumatic brain injury
- Journal of Chongqing Medical University Vol. 35, Issue 4, Pages: 637-638(2010)
- 作者机构：
  
  四川省内江市第一人民医院神经外科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2010.04.043
  CLC： R651.15
- Published：2010，
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[1]李兴华,刘丛.早期机械通气对重型颅脑损伤患者的疗效观察[J].重庆医科大学学报,2010,35(04):637-638.

LI Xing-hua, et al. Observation on therapeutic effects of early stage mechanical ventilation in treating acute severe traumatic brain injury. [J]. Journal of Chongqing Medical University 35(4):637-638(2010)
[1]李兴华,刘丛.早期机械通气对重型颅脑损伤患者的疗效观察[J].重庆医科大学学报,2010,35(04):637-638. DOI： 10.13406/j.cnki.cyxb.2010.04.043.

LI Xing-hua, et al. Observation on therapeutic effects of early stage mechanical ventilation in treating acute severe traumatic brain injury. [J]. Journal of Chongqing Medical University 35(4):637-638(2010) DOI： 10.13406/j.cnki.cyxb.2010.04.043.

摘要

目的:探讨早期机械通气对重型颅脑损伤患者的治疗作用。方法:将96例重型颅脑损伤患者随机分成A组:伤后早期使用机械通气（48例）;B组:伤后予以吸氧而未使用机械通气（48例）。进行两组间呼吸监测指标（PaO2、PaCO2、SaO2）、机械通气前后呼吸监测指标以及预后的对比分析。结果:A组机械通气后PaO2、PaCO2、SaO2等指标较B组有明显改善。A组在使用机械通气前后各呼吸监测指标亦有显著性差异（P<0.05）。6个月后按GOS预后判断

A组生存质量优于B组（P<0.05）。结论:早期机械通气能改善重型颅脑伤患者的预后转归。

Abstract

Objective:To explore the effect in severe craniocerebral injury patients treated by early stage mechanical ventilation.Methods:96 cases were randomly divided into two groups:48 cases in group A received early stage mechanicaI ventilation right after their admission;48 cases in group B received Oxygen instead of mechanical ventilation.Blood-gas indexes(PaO2

PaCO2

SaO)2of the two groups

before and after mechanical ventilation were monitored and prognosis of the patients were analyzed.Results:The indexes such as PaO2

PaCO2

SaO2 in Group A were much more improved than those of Group B.According to the GOS prognosis evaluation six months later

prognosis of patients in group A were superior to that of patients in group B(P<0.05).Conclusion:Early stage mechanical ventilation can improve the prognosis of severe craniocerebral injury patients with hyperventilation.

关键词

重型颅脑损伤机械通气治疗预后

Keywords

evere craniocerebral injurymechanical ventilationtherapyprognosis

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Related Institution

Laboratory of Basic Medical Science,General Hospital of Southern Theater Command of PLA

Department of Laboratory Medicine,General Hospital of Southern Theater Command of PLA

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Department of Neurology ， Chongging Emergency Medical Center

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