Clinical analysis of risk factors of post ischemic stroke seizure:a case-control study

ZHANG Mei-lin; et al

doi:10.13406/j.cnki.cyxb.2010.04.029

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Clinical analysis of risk factors of post ischemic stroke seizure:a case-control study

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- Clinical analysis of risk factors of post ischemic stroke seizure:a case-control study
- Journal of Chongqing Medical University Vol. 35, Issue 4, Pages: 608-612(2010)
- 作者机构：
  
  重庆医科大学附属第二医院神经内科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2010.04.029
  CLC： R742.1;R743.3
- Published：2010，
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[1]张美林,黄斌,陈阳美.缺血性卒中后癫痫发作危险因素的临床分析[J].重庆医科大学学报,2010,35(04):608-612.

ZHANG Mei-lin, et al. Clinical analysis of risk factors of post ischemic stroke seizure:a case-control study. [J]. Journal of Chongqing Medical University 35(4):608-612(2010)
[1]张美林,黄斌,陈阳美.缺血性卒中后癫痫发作危险因素的临床分析[J].重庆医科大学学报,2010,35(04):608-612. DOI： 10.13406/j.cnki.cyxb.2010.04.029.

ZHANG Mei-lin, et al. Clinical analysis of risk factors of post ischemic stroke seizure:a case-control study. [J]. Journal of Chongqing Medical University 35(4):608-612(2010) DOI： 10.13406/j.cnki.cyxb.2010.04.029.

摘要

目的:探讨缺血性卒中后癫痫发作的危险因素及临床特点以指导临床干预

进行合理治疗

改善预后。方法:缺血性卒中后继发癫痫发作组47例

未继发癫痫发作组50例

回顾性分析两组患者的临床资料

先对资料进行单因素分析

然后进行多因素Logistic回归分析。结果:单因素分析显示缺血性卒中类型、病灶部位、神经功能缺损评分（NIH Stroke Scacle

NIHSS）与卒中后癫痫发作有显著的相关性;多因素Logistic回归分析显示缺血性卒中亚型为心源性脑栓塞（OR=5.519

P=0.048）、病灶在皮质（OR=0.263

P=0.006）、NIHSS高（OR=0.873

P=0.046）3个因素为缺血性卒中后癫痫发作的危险因素。结论:具有缺血性卒中亚型为心源性脑栓塞、病灶部位在皮质、NIHSS高等因素的缺血性卒中患者易继发癫痫发作。

Abstract

Objective:To explore the risk factors and clinical features of post ischemic stroke seizure in order to direct clinical intervention

optimal treatment and improve prognosis.Methods:There were 47 patients with post ischemic stroke seizure

50 ischemic stroke patients without secondary seizure.The clinical data of them were reviewed.Multivariate stepwise logistic model analysis was made after univariate analysis.Results:Univariate analysis showed that lesion location

ischemic stroke subtype

NIHSS were associated with the development of seizures after ischemic stroke.Multivariate logistic regression analysis showed that cardioembolic infarction

cortical location

high NIHSS were independent risk factors for seizures after ischemic stroke.Conclusion:Post ischemic stroke patients who have cardioembolic infarction

cortical location

high NIHSS are likely to develop seizures.

关键词

缺血性卒中癫痫发作癫痫危险因素

Keywords

ischemic strokeSeizureepilepsyrisk factors

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Related Institution

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