LUO Su-xin, et al. Study on the relationship between cardiovascular risk factors and coronary artery disease. [J]. Journal of Chongqing Medical University 35(4):564-567(2010)
LUO Su-xin, et al. Study on the relationship between cardiovascular risk factors and coronary artery disease. [J]. Journal of Chongqing Medical University 35(4):564-567(2010) DOI: 10.13406/j.cnki.cyxb.2010.04.010.
Study on the relationship between cardiovascular risk factors and coronary artery disease
Objective:To analyze the relationship between conventional cardiovascular risk factors and coronary artery disease in Chongqing area.Methods:Three hundreds and ninety-eight patients were enrolled with a medical history in detail
a physical examination and biochemistry examination
who were diagnosed or suspected were performed by coronary angiography(CAG)
then these patients were divided into three groups according to the result of CAG
coronary heart disease(CHD)group(226 cases)
coronary arteriosclerosis(CAS)group(44 cases)and control group(CT)(128 cases).Toanalyze and compare the ratioofrisk factors in each group
univariate and multivariate logistic regression method were used respectively to analyze the relationship between risk factors and CHD or CAS group.Results:1.Compared with CT group
the percentage of hypertensive(HP)
type 2 diabetes mellitus(T2DM)
hyperlipidemia
smoking history and family history of cardiovascular disease was significantly higher in CHD group(P<0.05
more P<0.01).Men were more likely to suffer from CHD than women(P<0.05).There was no significant difference of body mass index(BMI)for these two groups.Compared with CT group
the percentage of HP and family history of cardiovascular disease was higher significantly in CAS group(P<0.05).But there was no significant difference with the other cardiovascular risk factors.There was no significant difference with the percentage of each risk factor between CHD group and CAS group(P>0.05).2.The distribution of risk factors in CHD group was the same as CAS group(P>0.05).3.The more cardiovascular risk factors
the more serious coronary artery disease.Conclusion:Besides BMI
conventional risk factors of cardiovascular contribute to coronary heart disease in this area
and they play an important and independent role in occurrence and progression of coronary artery disease.