Objective:To observe the clinical efficacy and safety of radiofrequency thermocoagulation on the treatment of primary trigeminal neuralgia guided with digital substraction angiography(DSA) in short-term

mid-term prospect.Methods:Twenty-seven patients of PTN were positioned by DSA

then treated with radiofrequency thermocoagulation.The VAS scores

clinical efficacy and complication were observed nearly post-treatment.The effects in mid-term was assessed in secondary follow-up.Results:All patients were punctured successfully.After treatment

all patients have pain relief.VAS scores on day 1

day 3

week 1 after radiofrequency thermocoagulation were 2.12±0.64

1.04±1.02

0.46±0.31 respectively

decreased compared with that before treatment(P<0.01)

and the satisfactory rate were 55.6%

74.1%

92.6% respectively.No serious complication occurred in all of the patients.22 patients were invovled in the follow-up survey 1 year after radiofrequency thermocoagulation

and the satisfactory rate was 86.4%

1 patient recurred

the recurrence rate was 4.5%.Conclusion:Radiofrequency thermocoagulation guided with DSA for the treatment of primary trigeminal neuralgia is effective and safe.