JIANG Cheng-cheng, et al. Impact on asthma by treatment of mometasone furoate monohydrate nasal spray to allergic rhinitis. [J]. Journal of Chongqing Medical University 35(3):467-469(2010)
JIANG Cheng-cheng, et al. Impact on asthma by treatment of mometasone furoate monohydrate nasal spray to allergic rhinitis. [J]. Journal of Chongqing Medical University 35(3):467-469(2010) DOI: 10.13406/j.cnki.cyxb.2010.03.013.
Impact on asthma by treatment of mometasone furoate monohydrate nasal spray to allergic rhinitis
Objective:To identify the impact on asthma by the treatment of mometasone furoate monohydrate nasal spray to allergic rhinitis.Methods:This was an opened own control study.25 patients with asthma and rhinitis were given inhaled-powder salmeterol/fluticasone50 μg/250 μg(Seretide)
one inhalation each time
twice daily via Diskhaler for 3 months.then added the use of mometasone furoate monohydrate nasal spray(Nasonex) 50 μg
one spray each nasal side each time
twice daily.To determine the efficacy of different treatment methods.The forced expiratory volume in one second(FEV1)
the forced vital capacity(FVC)
asthma symptom scores
nocturnal-awakening times and the amount of use of inhaled short-actingβ2-adrenoceptor agonist bronchodilators were observed respectively before the treatment
after the treatment of salmeterol/fluticasone 50 μg/250 μg for 3 months
and after the treatment of inhaled-powder salmeterol/fluticasone combined with Nasonex for 3 months.Results:The treatment of inhaled-powder salmeterol/fluticasone combined with mometasone furoate monohydrate nasal spray improved FEV1
FVC and clinical asthma symptoms
and decreased the amount of the use of inhaled short-actingβ2-adrenoceptor agonist bronchodilators
there were significant differences(P<0.05).Conclusion:The treatment to allergic rhinitis by mometasone furoate monohydrate nasal spray improved the efficacy of the treatment to asthma.