Objective:To explore the perioperative treatment principle for arteriovenous fistulas of hemodialysis

the related factors to the success of operations and the intervention measures.Methods:1820 cases in the 2 periods from 1992to 2000 and from 2001 to 2008 were selected

and the relation of the change of primary diseases

the difference of their blood vessel condition before operation

different operation methods and different treatment after operation to the successful rate of operation and fistulas blood flow was analyzed and statistical analysis was made to the related data.Results:The ratio of secondary renal disease in the second period was much bigger and of significant difference with that in the first period(P<0.01);the factors to decide the success of operation included primary disease

the protection of peripheral vessels of upper limbs before operation

the right time to set up fistulas

methods of anastomosis and post-operation treatment measures;the blood flow was correlated to the operation methods

the blood flow after mature formation fistulas anastomosed with cyclic titanium nail was 210.20±45.42 ml/min

the blood flow after mature formation fistulas anastomozed with end-to-end neurorrhaphy was 281.10±27.57 ml/min while that with end-to-side neurorrhaphy was 323.40±ml/min

there existed a statistical difference among the 3 methods(P<0.05).Conclusions:Time going leads to the change of primary diseases in patients with chronic renal failure

and then to the changes of blood vessels and the inner circumstances in patients of fistulization;the increase of the successful rate of operation should not only depend on performance skills

but also on each link in perioperative period

including the protection of blood vessels before operation

the selection of blood vessels for fistulization

the selection of operation methods

the performance in operation and the treatment of anticoagulation and antiplatelet.