Effect of propofol-remifentanil infusion combined with sevoflurane inhalation in the wake-up test during posterior spinal infusion surgery

LI Qi-ying; et al

doi:10.13406/j.cnki.cyxb.2010.02.020

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Effect of propofol-remifentanil infusion combined with sevoflurane inhalation in the wake-up test during posterior spinal infusion surgery

更新时间：2024-01-17

- Effect of propofol-remifentanil infusion combined with sevoflurane inhalation in the wake-up test during posterior spinal infusion surgery
- Journal of Chongqing Medical University Vol. 35, Issue 2, Pages: 265-267(2010)
- 作者机构：
  
  重庆医科大学附属第一医院麻醉科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2010.02.020
  CLC： R614.2
- Published：2010，
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[1]李琪英,闵苏.丙泊酚-瑞芬太尼-七氟烷麻醉在脊柱侧弯矫形术术中唤醒试验的应用[J].重庆医科大学学报,2010,35(02):265-267.

LI Qi-ying, et al. Effect of propofol-remifentanil infusion combined with sevoflurane inhalation in the wake-up test during posterior spinal infusion surgery. [J]. Journal of Chongqing Medical University 35(2):265-267(2010)
[1]李琪英,闵苏.丙泊酚-瑞芬太尼-七氟烷麻醉在脊柱侧弯矫形术术中唤醒试验的应用[J].重庆医科大学学报,2010,35(02):265-267. DOI： 10.13406/j.cnki.cyxb.2010.02.020.

LI Qi-ying, et al. Effect of propofol-remifentanil infusion combined with sevoflurane inhalation in the wake-up test during posterior spinal infusion surgery. [J]. Journal of Chongqing Medical University 35(2):265-267(2010) DOI： 10.13406/j.cnki.cyxb.2010.02.020.

摘要

目的:评价以丙泊酚瑞芬太尼输注复合七氟烷吸入麻醉方法在脊柱侧弯矫形手术术中唤醒试验的特点。方法:20例脊柱侧弯患者拟行脊柱后路融合手术。瑞芬太尼

丙泊酚和阿曲库铵诱导

以瑞芬太尼0.2μg/（kg·min）和丙泊酚50μg/（kg·min）持续静脉泵注

同时吸入2%七氟烷维持麻醉

间断给予阿曲库铵保持适当的肌肉松弛。手术医师要求唤醒前20min

停止泵注瑞芬太尼、丙泊酚和七氟烷吸入。呼唤病人活动手足

记录停药到患者自主呼吸恢复的时间（T

）

自主呼吸恢复到手足运动的时间（T

）

并评价唤醒试验的质量

同时记录麻醉前、诱导后、停药即刻、唤醒即刻、加深麻醉后的血流动力学变化。结果:患者唤醒即刻的平均动脉压（Mean arterial pressure

MAP）、心率（Heart rate

HR）与停药即刻比较无明显升高（P

0.05）

和T

分别为（4.1±2.0）min和（4.5±2.2）min。18位患者的唤醒试验质量达到满意及以上标准。结论:丙泊酚-瑞芬太尼-七氟烷复合麻醉在脊柱侧弯矫形术中可实现安全快速的唤醒。

Abstract

Objective:To assess the characteristics of the wake-up test during compound propofol-remifentanil infusions and sevoflurane inhalation for posterior spinal infusion（PSF）surgery.Methods:Twenty patients with scoliosis and candidates for PSF surgery were studied.After an i.v.bolus of remifentanil 1μg/kg

anesthesia was induced with propofol and atracurium.During maintenance

all patients received infusion of remifentanil 0.2μg/（kg·min）and propofol 50μg（kg·min）and inhalation of 2%sevoflurane.Atracurium was given to maintain the required surgical relaxation.At the surgeon’s request

all infusions were discontinued.Patients were asked to move their hands and feet.Time from anesthetic discontinuation to spontaneous ventilation（T

）

and from then until movement of the hands and feet （T

）

its quality and hemodynamics were recorded.Results:T

and T

were（4.1±2.0）minutes and（4.5±2.2）minutes

respectively. Quality of wake-up test reached satisfactory or good standard in 18 patients.Conclusion:wake-up test can be conducted fast and safely with propfol and remifentanil compound inhalation sevoflurane.

关键词

丙泊酚瑞芬太尼七氟烷唤醒试验脊柱侧弯矫形

Keywords

propofolremifentanilsevofluraneWake-up testKyphoscoliosis

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