A clinical analysis of synthetic therapy effect and prognostic factors in 107 patients with breast cancer

ZHUANG Xiu-fen; et al

doi:10.13406/j.cnki.cyxb.2010.01.036

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A clinical analysis of synthetic therapy effect and prognostic factors in 107 patients with breast cancer

更新时间：2024-01-17

- A clinical analysis of synthetic therapy effect and prognostic factors in 107 patients with breast cancer
- Journal of Chongqing Medical University Vol. 35, Issue 1, Pages: 130-134(2010)
- 作者机构：
  
  1. 重庆医科大学附属第一医院肿瘤科
  2. 重庆医科大学附属第二医院肿瘤科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2010.01.036
  CLC： R737.9
- Published：2010，
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[1]庄秀芬,张幸平,郭慧琳,张玲,甘露,邓红彬.107例乳腺癌患者综合治疗的疗效及预后分析[J].重庆医科大学学报,2010,35(01):130-134.

ZHUANG Xiu-fen, et al. A clinical analysis of synthetic therapy effect and prognostic factors in 107 patients with breast cancer. [J]. Journal of Chongqing Medical University 35(1):130-134(2010)
[1]庄秀芬,张幸平,郭慧琳,张玲,甘露,邓红彬.107例乳腺癌患者综合治疗的疗效及预后分析[J].重庆医科大学学报,2010,35(01):130-134. DOI： 10.13406/j.cnki.cyxb.2010.01.036.

ZHUANG Xiu-fen, et al. A clinical analysis of synthetic therapy effect and prognostic factors in 107 patients with breast cancer. [J]. Journal of Chongqing Medical University 35(1):130-134(2010) DOI： 10.13406/j.cnki.cyxb.2010.01.036.

摘要

目的:回顾性研究107例乳腺癌患者综合治疗的疗效、预后及其影响因素。方法:收集2000年1月至2003年12月在我科行术后放射治疗的107例乳腺癌患者的临床及病理资料

探讨患者年龄、绝经情况、肿瘤大小、腋淋巴结转移情况、TNM分期、激素受体表达、内分泌治疗疗效与预后的相关性。结果:本组病例平均总生存时间（Overall survival

OS）及无病生存时间（Disease-freesurvival

DFS）分别是90.3月和74.8月。与乳腺癌患者预后有关的因素是肿瘤大小、腋淋巴结转移数目及TNM分期（P值均<0.05）;而患者年龄、绝经状况、激素受体表达和内分泌治疗与否对乳腺癌患者的预后无显著性影响（P值均>0.05）。结论:原发肿瘤大小、腋淋巴结转移情况及TNM分期与乳腺癌患者的预后密切相关

而年龄、绝经状况、激素受体状态和内分泌治疗与否与患者预后无明显相关。

Abstract

Objective:To investigate the synthetic therapy effect and prognosticfactorsin 107 patientswith breastcancer and explore the relationship between some clinical-pathological factors and patients’ prognosis.Methods:Between Jan

2000 and Dec

2003

the clinical-pathological materials of 107 breast cancer cases who have received synthetic therapy

including radiotherapy

surgery

chemotherapy and endocrine therapy

were analyzed.The correlation of age

menopausal status

tumor size

axillary lymph nodal status

TNM stage

hormone receptor status and endocrinetherapy with prognosis of breast cancer was evaluated.Results:The overall survival and disease-free survival of the whole patients were 90.3 and 74.8 months

respectively.Analysis revealed that overall survival and disease-free survival of this group were significantly associated with tumor size

axillary lymph nodal status and TNMstage(P<0.05).Patients’age

menopause status

hormone receptor status and endocrine therapy had no significant independent prognostic value(P>0.05).Conclusion:Our data demonstrate that tumor size

axillary lymph nodal status and TNM stage are significant independent indicators of prognosis in breast cancer respectively

and age

menopausal status

hormone receptor status and endocrine therapy are not significant factors of prognosis.

关键词

乳腺癌综合治疗预后

Keywords

breast cancerSynthetic therapyprognosis

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Related Institution

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