Study on recovery action of Buflomedil Hydrochloride to peripheral nerve crush lesion in rats

SU Jianhua; et al

doi:10.13406/j.cnki.cyxb.2007.12.034

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Study on recovery action of Buflomedil Hydrochloride to peripheral nerve crush lesion in rats

更新时间：2024-01-17

- Study on recovery action of Buflomedil Hydrochloride to peripheral nerve crush lesion in rats
- Journal of Chongqing Medical University Issue 12, Pages: 1246-1248(2007)
- 作者机构：
  
  1. 江苏省金坛市人民医院神内科
  2. 江苏省常州市第四人民医院病理科
  3. 南京医科大学附属第一医院神内科
  4. 南京医科大学神经毒理学院
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2007.12.034
  CLC： R96
- Published：2007，
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[1]苏建华,章莉萍,陈玉芳,唐金荣,肖杭,包德诚.盐酸丁咯地尔对实验SD大鼠坐骨神经损害恢复的影响[J].重庆医科大学学报,2007(12):1246-1248.

SU Jianhua, et al. Study on recovery action of Buflomedil Hydrochloride to peripheral nerve crush lesion in rats. [J]. Journal of Chongqing Medical University (12):1246-1248(2007)
[1]苏建华,章莉萍,陈玉芳,唐金荣,肖杭,包德诚.盐酸丁咯地尔对实验SD大鼠坐骨神经损害恢复的影响[J].重庆医科大学学报,2007(12):1246-1248. DOI： 10.13406/j.cnki.cyxb.2007.12.034.

SU Jianhua, et al. Study on recovery action of Buflomedil Hydrochloride to peripheral nerve crush lesion in rats. [J]. Journal of Chongqing Medical University (12):1246-1248(2007) DOI： 10.13406/j.cnki.cyxb.2007.12.034.

摘要

目的:观察盐酸丁咯地尔对周围神经损害后恢复的影响。方法:以SD大鼠坐骨神经建立周围神经损害动物模型

以坐骨神经传导速度、坐骨神经干病理切片（光镜、电镜）为观察指标

考察盐酸丁咯地尔对周围神经损害后恢复的影响。结果:盐酸丁咯地尔组给药4周后能显著改善大鼠坐骨神经损害。结论:盐酸丁咯地尔对周围神经损害有确切的修复作用。

Abstract

Objective: study on recovery action of Buflomedil Hydrochloride to peripheral nerve crush lesion in rats. Methods: Sciatic nerve crush lesion model were established in rats

The conduction velocity of sciatie nerve and the morphological changes were observed by light and electron. Results:At the end of 4 weeks

Buflomedil Hydrochloride can obviously recover the sciatic crash lesion in rats. Conclusion:Buflomedil Hydrochloride shows recovery effect on the peripheral crush lesion.

关键词

盐酸丁咯地尔周围神经损害修复作用

Keywords

Buflomedil HydrochloridePeripheral nerve crush lesionReeovery action

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Related Author

ZHANG Liping

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陈玉芳

唐金荣

肖杭

包德诚

Related Institution

Department of Pediatrics,the People’s Hospital of Jintan

金坛市人民医院神经内科

常州市第四人民医院病理科

南京医科大学附属第一医院神经内科

南京医科大学应用神经毒理研究所

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