Objective:The purpose of this study is to evaluate the clinical efficacy of remifentanil combined with proopofol in the course of anesthesia induction and analepsia. Methods: 90 ASAⅠ～Ⅱpatients excision of tumor of the ovary and salphingectomy undergoing gynaecologic laparoscopy were randomly divided into two groups:R group (propofol and vemifentanil n=45) and F group (propofol and fentanil n=45).MAP and HR were observed at the time of anesthesia induction tracheal intubation;the time of spontaneuusly breathing

awakeness

extubation

orientation force and the time of PACU were record;we view the patient of conscious state

cognition functional and the degree of pain;and observe the side effects of nausea and vomitting

intraoperative awareness and degree of patients’satisfaction. Result:There was no significant diference in decrease of two group of MAP in the course of anesthesia. The rate of cardiovascular response to tracheal intubation in F group is higher than that in R group

and hemobynamics was stabler. There was significantly diference in the time of spontaneously breathing

awakeness and extubation. At the time instant extubation and departing PACU were shorter

VAS after extubation 1h in R group was higher than that in F group. There was no significant diference in incidence rate of postoperative nausea and vomitting. Conclusion: Awake qualily of intravenous anesthesia with Propofol and remifentanil was better than that with Propofol and fentanil in excision of tumor of the ovary and salpingectomy undergoing gynaecologic laparoscopy. As half life of remifentanil was short

patients felt pain soon after operation and pestoperative analgesia should be performed promptly.