Objective:To search a dissolvent which can relive the pain for intramuscular injection of penicillin.Methods:100 pa- tients were randomly divided into two groups

each had 50 patients.all individuals had normal aesthema and speaking ability

the serious failure ones and patients who had used sedatives or pain-killer recently were not brought into the study.Use 0.9% sodium chloride solution as dissolvant for intramuscular injection of penicillin in experimental group

Sterile Water for Injection in the control group.Observe the subjects’focal pain and general reaction after injected.Results:subjects injected with 0.9% sodium chloride solution as dissolvant had less pain and general reaction

the rate of acupuncture syncope was reduced.Conclu- sion:Use 0.9%sodium chloride solution as dissolvant for intramuscular injection of penicillin can efficaciously relieve patients’ focal pain and general reaction

reduce the rate of acupuncture syncope.It’s a safe dissolvant.