Expression and significance of survivin in endometriosis

Wangjia

doi:10.13406/j.cnki.cyxb.2005.06.017

您当前的位置：

首页 >

文章列表页 >

Expression and significance of survivin in endometriosis

更新时间：2024-01-17

- Expression and significance of survivin in endometriosis
- Journal of Chongqing Medical University Issue 6, Pages: 843-845(2005)
- 作者机构：
  
  1. 重庆医科大学附属第一医院妇产科
  2. 重庆医科大学附属第一医院妇产科,重庆,400016
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2005.06.017
  CLC： R711.71
- Published：2005，
扫描看全文
[1]王佳,唐良萏,姚珍薇.Survivin在子宫内膜异位症的表达及意义[J].重庆医科大学学报,2005(06):843-845.

Wangjia. Expression and significance of survivin in endometriosis. [J]. Journal of Chongqing Medical University (6):843-845(2005)
[1]王佳,唐良萏,姚珍薇.Survivin在子宫内膜异位症的表达及意义[J].重庆医科大学学报,2005(06):843-845. DOI： 10.13406/j.cnki.cyxb.2005.06.017.

Wangjia. Expression and significance of survivin in endometriosis. [J]. Journal of Chongqing Medical University (6):843-845(2005) DOI： 10.13406/j.cnki.cyxb.2005.06.017.

摘要

目的:探讨凋亡抑制基因survivin在子宫内膜异位症中的表达及意义。方法:应用免疫组织化学链霉素抗生物素蛋白-过氧化酶连接法（SP法）

检测40例子宫内膜异位症异位子宫内膜组织中survivin蛋白的表达

并与正常在位子宫内膜组织25例进行对照。结果:子宫内膜异位症异位内膜组织中survivin蛋白阳性表达率为67．5％

明显高于正常在位内膜组织的阳性表达率4．2％（P<0．01）

并且异位内膜组织中survivin蛋白表达与月经周期无相关性（P>0．05）。结论:survivin在子宫内膜异位症异位内膜中高表达。并且可能通过抑制异位内膜细胞凋亡

对子宫内膜异位症的发生、发展起作用。

Abstract

Objective: To study the expression of apoptosis related gene survivin in endometriosis. Methods; Expressions of survivin protein were detected by immunohistochemical method (SP) in 40 cases of endometriosis

and compared with those in 25 cases of normal eutopic endometrium. The correlation between them was analyzed. Results; The expression rate of survivin protein in endometriotic ec-topic cells was much higher than that in normal eutopic cells(P <0. 01 )

and was not correlated with menstrual cycle phase ( P > 0. 05). Conclusion: Survivin may play an important role in pathogenesis of endometriosis.

关键词

子宫内膜异位症Survivin细胞凋亡

Keywords

endometriosisSurvivinapoptosis

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Survivin expression in ovarian cancer and its associationwith tumor cellular apoptosis

The expression of survivin and its relationship with the expression of bcl-2 and bax protein in glioma

Expression and significance of survivin in meningiomas

Molecular mechanism of Buzhong Yiqi Decoction in coordination with Siβ-catenin in intervention against cisplatin resistance in lung adenocarcinoma by regulating the Wnt/β-catenin signaling pathway

Effect of Glycyrrhiza uralensis Fisch. endophytes combined with cisplatin on proliferation and apoptosis of A549 cells

Related Author

SHU Wen

et al

SHI Quanhong

et al

SHI Quanhong

et al

秦保平

Li He

Related Institution

Department of Obstetrics and Gynecology,the Second Affilated Hospital,Chongqing Medical University

四川大学华西第二医院

Department of Neurosurgery,College of Clinical Medicine,Chongqing Medical University

重庆医科大学临床学院神经外科

Department of Neurosurgery,the First Affiliated Hospital,Chongqing Medical University

⁰