The relationship between serum adiponectin and high sensitivity C - reactive protein in patients with acute coronary syndrome

LUO suxin; et al

doi:10.13406/j.cnki.cyxb.2005.06.005

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The relationship between serum adiponectin and high sensitivity C - reactive protein in patients with acute coronary syndrome

更新时间：2024-01-17

- The relationship between serum adiponectin and high sensitivity C - reactive protein in patients with acute coronary syndrome
- Journal of Chongqing Medical University Issue 6, Pages: 791-793(2005)
- 作者机构：
  
  1. 重庆医科大学附属第一医院心内科
  2. 重庆医科大学附属第一医院临床研究中心
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2005.06.005
  CLC： R541.4
- Published：2005，
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[1]罗素新,雷寒,马康华,柳青.急性冠脉综合征患者血清脂联素与高敏C反应蛋白的关系[J].重庆医科大学学报,2005(06):791-793.

LUO suxin, et al. The relationship between serum adiponectin and high sensitivity C - reactive protein in patients with acute coronary syndrome. [J]. Journal of Chongqing Medical University (6):791-793(2005)
[1]罗素新,雷寒,马康华,柳青.急性冠脉综合征患者血清脂联素与高敏C反应蛋白的关系[J].重庆医科大学学报,2005(06):791-793. DOI： 10.13406/j.cnki.cyxb.2005.06.005.

LUO suxin, et al. The relationship between serum adiponectin and high sensitivity C - reactive protein in patients with acute coronary syndrome. [J]. Journal of Chongqing Medical University (6):791-793(2005) DOI： 10.13406/j.cnki.cyxb.2005.06.005.

摘要

目的:探讨急性冠状动脉综合征（ACS）患者血清脂联素与高敏C反应蛋白（hsCRP）的关系。方法:收集行冠状动脉造影术的冠心病患者90例

其中急性心肌梗死（AMI）41例

不稳定性心绞痛（UAP）27例;稳定性心绞痛（SAP）22例

健康对照组20例。采用酶联免疫吸附法（ELISA）测定血清脂联素

采用免疫散射比浊法测定hsCRP。结果:ACS组血清脂联素浓度显著低于SAP组（P<0．05）和对照组（P<0．01）

hsCRP浓度显著高于SAP组（P<0．05）和对照组（P<0．01）

且ACS组血清脂联素与hsCRP呈负相关（r=-0．33

P<0．05）。结论:脂联素具有抗炎、抗动脉粥样硬化的保护作用

对ACS的发生和发展有一定的预测价值。

Abstract

Objective:To investigate the relationship between serum adiponectin and high sensitivity C - reactive protein( hsCRP) in patients with acute coronary syndrome ACS). Methods; Serum adiponectin were measured by enzyme linked immunosorbent assay in patients with acute myocardial infarction(n =41 ) .unstable angina pectoris(n = 27)

stable angina pectoris(n =22) and control group (n =20) . Their serum hsCRP were measured by scatter velocity turbidimethy. All subjects were confirmed by coronary angiography. Results ; Serum adiponectin concentrations in ACS group were significantly lower than those in SAP group) P <0. 05 ) and control group (P<0.01 )

accompanied with higher hsCRP ( P < 0. 05

P < 0. 01 ) . Serum adiponectin concentrations were correlated negatively with hsCRP ( r =- 0. 33

P < 0. 05 ). Conculusion; Adiponectin have anti - inflammatory and anti - atherogenic properties

which may play a predictive value for the origin and development of ACS.

关键词

急性冠状动脉综合征脂联素高敏C反应蛋白

Keywords

acute coronary syndromeadiponectinHigh sensitivity C - reactive protein

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