To choose the prescription of the optimum testosterone propionate frost and the production craft condition with orthogonal test

DU Su; et al

doi:10.13406/j.cnki.cyxb.2005.03.045

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To choose the prescription of the optimum testosterone propionate frost and the production craft condition with orthogonal test

更新时间：2024-01-17

- To choose the prescription of the optimum testosterone propionate frost and the production craft condition with orthogonal test
- Journal of Chongqing Medical University Issue 3, Pages: 463-464(2005)
- 作者机构：
  
  1. 重庆医科大学儿科学院药剂科
  2. 重庆医科大学儿科学院药剂科,重庆,400014
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2005.03.045
  CLC： TQ463
- Published：2005，
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[1]杜甦,冉萍.正交实验法优选睾酮霜的配方及生产工艺条件[J].重庆医科大学学报,2005(03):463-464.

DU Su, et al. To choose the prescription of the optimum testosterone propionate frost and the production craft condition with orthogonal test. [J]. Journal of Chongqing Medical University (3):463-464(2005)
[1]杜甦,冉萍.正交实验法优选睾酮霜的配方及生产工艺条件[J].重庆医科大学学报,2005(03):463-464. DOI： 10.13406/j.cnki.cyxb.2005.03.045.

DU Su, et al. To choose the prescription of the optimum testosterone propionate frost and the production craft condition with orthogonal test. [J]. Journal of Chongqing Medical University (3):463-464(2005) DOI： 10.13406/j.cnki.cyxb.2005.03.045.

摘要

目的:优选睾酮霜的基质配方及生产工艺条件。方法:以乳膏剂的稳定性及外观性状为考察指标

采用正交设计法进行实验。以油相配比、乳膏剂用量、主药的加入方式为可变因素。结果:最优的基质配方及工艺为A1B2C2或A1B3C3。结论:制备的睾酮霜符合中国药典2000版有关软膏剂的规定[1]。

Abstract

Objective:To choose the prescription of the optimum testosterone propionate frost and the production craft conditions.Methods:Take the stability and the external appearance forms of the creams as the index sign to be checked

and carry out the experiment with orthogonal test.With the oil matches each other the ratio

the creams dosage

the way to add the main medicine a variable factor.Results:The superior formulation and craft are A 1B 2C 2 or A 1B 3C 3.Conclusion:The ready frost of testosterone propionate meets the provision of the Chinese Medical Dictionary 2000 on relevant ointments.

关键词

正交实验睾酮霜基质配方工艺条件

Keywords

Orthogonal testFrost of testosterone propionateBases prescriptionCraft condition

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