Clinical analysis of malignant ovarian germ cell tumor

CHEN Xiaofen; et al

doi:10.13406/j.cnki.cyxb.2005.03.042

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Clinical analysis of malignant ovarian germ cell tumor

更新时间：2024-01-17

- Clinical analysis of malignant ovarian germ cell tumor
- Journal of Chongqing Medical University Issue 3, Pages: 456-458(2005)
- 作者机构：
  
  1. 川北医学院附属医院妇产科
  2. 重庆医科大学临床学院妇产科,四川,南充,637000
  3. ,重庆,400016
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2005.03.042
  CLC： R737.31
- Published：2005，
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[1]陈小芬,梅耀宇,叶之美.卵巢恶性生殖细胞肿瘤的临床分析[J].重庆医科大学学报,2005(03):456-458.

CHEN Xiaofen, et al. Clinical analysis of malignant ovarian germ cell tumor. [J]. Journal of Chongqing Medical University (3):456-458(2005)
[1]陈小芬,梅耀宇,叶之美.卵巢恶性生殖细胞肿瘤的临床分析[J].重庆医科大学学报,2005(03):456-458. DOI： 10.13406/j.cnki.cyxb.2005.03.042.

CHEN Xiaofen, et al. Clinical analysis of malignant ovarian germ cell tumor. [J]. Journal of Chongqing Medical University (3):456-458(2005) DOI： 10.13406/j.cnki.cyxb.2005.03.042.

摘要

目的:探讨卵巢恶性生殖细胞肿瘤的临床特点、治疗及预后。方法:对38例卵巢恶性生殖细胞肿瘤（卵黄囊瘤15例、无性细胞瘤10例、未成熟畸胎瘤9例、成熟畸胎瘤恶变4例）进行回顾性分析。结果:患者中位年龄25岁（11～54岁）;FIGO临床分期:Ⅰ期18例（47.4%）

Ⅱ期及Ⅲ期各7例（18.4%）

Ⅳ期2例（5.3%）

复发4例（10.5%）。全组总的2年生存率为76.3%

Ⅰ、Ⅱ期患者为96.0%。保留生育功能有生育要求的6例

娩出4例健康新生儿。结论:卵巢恶性生殖细胞肿瘤治愈率明显提高

临床分期及治疗方式是重要的预后因素

保守性手术及生育功能的保留是可行的。

Abstract

Objective:To evaluate the clinical profile

treatment methods

and prognosis for malignant germ cell tumors of the ovary.Methods:A total of 38 patients with malignant ovarian germ cell tumors(15 yolk sac tumors

10 dysgerminomas

9 immature teratomas

and 4 mature cystic teratomas with malignant transformation)were analyzed retrospectively.Results:The median age of the patients was 25 years(range 11～54).There were 18 FLGO stage Ⅰ tumors (47.4%)

7 stage Ⅱ and Ⅲ tumors respectively(18.4%)

2 stage Ⅳ tumors (5.3%)

and 4 recurrent tumors (10.5%).The overall 2-year survival rate was 76.3%

the survival rate of patients with stageⅠ-Ⅱdisease was 96.0%.Of the cases who preserved fertility

6 patients had the desire of fertility

4 healthy live births were recorded.Conclusion:The cure rate of malignant ovarian germ cell tumors has improved greatly.The staging and treatment approaches are important prognostic factors.Conservative surgery and preservation of fertility are feasible.

关键词

卵巢恶性生殖细胞肿瘤治疗预后

Keywords

Malignant ovarian germ cell tumorstreatmentprognosis

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