Observation of clinical efficacy on treating psoriasis with zinc pyrithione spray and camptothecine cream

ZHOU Xun; et al

doi:10.13406/j.cnki.cyxb.2005.01.027

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Observation of clinical efficacy on treating psoriasis with zinc pyrithione spray and camptothecine cream

更新时间：2024-01-17

- Observation of clinical efficacy on treating psoriasis with zinc pyrithione spray and camptothecine cream
- Journal of Chongqing Medical University Issue 1, Pages: 95-97(2005)
- 作者机构：
  
  1. 重庆医科大学临床学院皮肤科
  2. 重庆医科大学临床学院皮肤科,重庆,400016
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2005.01.027
  CLC： R758.63
- Published：2005，
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[1]周汛,李惠.吡啶硫锌气雾剂与羟基喜树碱软膏治疗银屑病临床对比观察[J].重庆医科大学学报,2005(01):95-97.

ZHOU Xun, et al. Observation of clinical efficacy on treating psoriasis with zinc pyrithione spray and camptothecine cream. [J]. Journal of Chongqing Medical University (1):95-97(2005)
[1]周汛,李惠.吡啶硫锌气雾剂与羟基喜树碱软膏治疗银屑病临床对比观察[J].重庆医科大学学报,2005(01):95-97. DOI： 10.13406/j.cnki.cyxb.2005.01.027.

ZHOU Xun, et al. Observation of clinical efficacy on treating psoriasis with zinc pyrithione spray and camptothecine cream. [J]. Journal of Chongqing Medical University (1):95-97(2005) DOI： 10.13406/j.cnki.cyxb.2005.01.027.

摘要

目的评价吡啶硫锌气雾剂治疗银屑病的疗效和安全性。方法将48例银屑病患者随机分为试验组吡啶硫锌气雾剂和对照组羟基喜树碱软膏

疗程均为28天。结果治疗组与对照组有效率分别为86.4%和68.2%

两组有效率比较无显著性差异（P=0.150）。吡啶硫锌气雾剂治疗组不良反应发生率低且反应轻微。结论吡啶硫锌气雾剂治疗银屑病疗效确切

安全性好。

Abstract

Objective:To evalute the efficacy and safty of zinc pyrithione spray against psoriasis.Methods:48 patients with psoriasis were randomly assigned to receive either zinc pyrithione spray or camptothecine cream for 28 days.Results:There were no statistically significant differences between the two groups in terms of clinical efficacy ( P =0.150).Adverse effects were lower and mild in the zinc pyrithione spray group.Conclusion:The study indicates that zinc pyrithione spray is well-tolerated and effecitive for the treatment of psoriasis.

关键词

银屑病吡啶硫锌气雾剂羟基喜树碱软膏

Keywords

psoriasisZinc pyrithione sprayCamptothecine cream

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Related Institution

Centre of Neuroscience，Chongqing Medical University

Department of Dermatology，The First Affiliated Hospital of Chongqing Medical University

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Department of Dermatology，the First Affiliated Hospital，Liaoning Medical University

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