Relationship among serum uric acid,C-reactive protein and the degree of carotid artery atherosclerosis in patients with essential hypertension

LIU Dong; et al

doi:10.13406/j.cnki.cyxb.2005.01.016

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Relationship among serum uric acid,C-reactive protein and the degree of carotid artery atherosclerosis in patients with essential hypertension

更新时间：2024-01-17

- Relationship among serum uric acid,C-reactive protein and the degree of carotid artery atherosclerosis in patients with essential hypertension
- Journal of Chongqing Medical University Issue 1, Pages: 57-59(2005)
- 作者机构：
  
  1. 重庆医科大学第二临床学院心内科
  2. 重庆医科大学第二临床学院心内科,重庆,400010
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2005.01.016
  CLC： R543;R544.1
- Published：2005，
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[1]刘东,刘增长,殷跃辉,高大中.原发性高血压患者颈动脉粥样硬化与血尿酸及C反应蛋白的关系[J].重庆医科大学学报,2005(01):57-59.

LIU Dong, et al. Relationship among serum uric acid,C-reactive protein and the degree of carotid artery atherosclerosis in patients with essential hypertension. [J]. Journal of Chongqing Medical University (1):57-59(2005)
[1]刘东,刘增长,殷跃辉,高大中.原发性高血压患者颈动脉粥样硬化与血尿酸及C反应蛋白的关系[J].重庆医科大学学报,2005(01):57-59. DOI： 10.13406/j.cnki.cyxb.2005.01.016.

LIU Dong, et al. Relationship among serum uric acid,C-reactive protein and the degree of carotid artery atherosclerosis in patients with essential hypertension. [J]. Journal of Chongqing Medical University (1):57-59(2005) DOI： 10.13406/j.cnki.cyxb.2005.01.016.

摘要

目的探讨原发性高血压患者颈动脉粥样硬化的程度与血尿酸及C反应蛋白的关系。方法122例原发性高血压患者按颈动脉粥样硬化的程度分为内膜中膜增厚组（Ⅰ组）

斑块形成组（Ⅱ组）和管腔狭窄组（Ⅲ组）

分别测定其血尿酸及C反应蛋白的浓度

观察血尿酸与C反应蛋白的关系。结果斑块形成组和管腔狭窄组的血尿酸及C反应蛋白的浓度显著高于内膜中膜增厚组（P<0.05）

血尿酸亦与C反应蛋白呈正相关（r=0.45

P<0.01）。结论血尿酸及C反应蛋白与颈动脉粥样硬化的程度正相关。血尿酸可能是通过促炎症作用导致动脉粥样硬化。

Abstract

Objective:To investigate the relationship among serum uric acid

C-reactive protein and the degree of carotid artery atherosclerosis in patients with essential hypetension.Methods:122 patients with essential hypertension were divided into intima-media thickness group(Ⅰ)

plaque development group(Ⅱ) and vessel stenosis group(Ⅲ).Concentration of serum uric acid and C-reactive protein were measured in each patient and the relationship between serum uric acid and C-reactive protein was observed.Results:The concentrations of serum uric acid and C-reactive protein in group Ⅱ and Ⅲ were positively connected with pathologic changes of carotid artery atherosclerosis( P <0.05).The concentration of serum uric acid had a positive relation to that of C-reactive protein( r =0.45

P <0.01).Conclusion:The concentrations of serum uric acid and C-reactive protein have a positive relation to the degree of carotid artery atherosclerosis.

关键词

高血压动脉粥样硬化血尿酸C反应蛋白

Keywords

hypertensionatherosclerosisSerum uric acidC-reactive protein

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