Research and preparation of cyclosporine A eyedrops

ZOU liuyi; et al

doi:10.13406/j.cnki.cyxb.2004.05.042

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Research and preparation of cyclosporine A eyedrops

更新时间：2024-01-17

- Research and preparation of cyclosporine A eyedrops
- Journal of Chongqing Medical University Issue 5, Pages: 696-698(2004)
- 作者机构：
  
  1. 重庆医科大学临床学院药剂科
  2. 重庆医科大学附属口腔医院药剂科
  3. 重庆医科大学临床学院药剂科,重庆,400016
  4. ,重庆,400001
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2004.05.042
  CLC： R943
- Published：2004，
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[1]左六一,解新,赵语,王晓江.环孢素A滴眼液的研制[J].重庆医科大学学报,2004(05):696-698.

ZOU liuyi, et al. Research and preparation of cyclosporine A eyedrops. [J]. Journal of Chongqing Medical University (5):696-698(2004)
[1]左六一,解新,赵语,王晓江.环孢素A滴眼液的研制[J].重庆医科大学学报,2004(05):696-698. DOI： 10.13406/j.cnki.cyxb.2004.05.042.

ZOU liuyi, et al. Research and preparation of cyclosporine A eyedrops. [J]. Journal of Chongqing Medical University (5):696-698(2004) DOI： 10.13406/j.cnki.cyxb.2004.05.042.

摘要

目的 :建立了环孢素A滴眼液的制备方法。方法 :采用蓖麻油制备环孢素A滴眼液

用HLPC测定制剂中环孢素A的含量

并对制剂的稳定性进行了考察。结果 :本研究研制的环孢素A滴眼液制备工艺简单

质量稳定

含量测定快速、准确。结论 :该制剂工艺可用于常规制备环孢素A滴眼液

Abstract

Objective:To establish the prescription and preparing procedure for the cyclosporine A eyedrops.Methods:The cyclosporine A eyedrops was prepared from castor oil.The cyclosporine A content of the preparation was determined by HPLC

and stability of the preparation was examined

too.Results:The results showed the procedure of preparation was simple

and the quantitative determination was quick

and accurate while the quality was reliable.Conclusion:The procedure described here can be uesed to prepare the cyclosporine A eyedrops.

关键词

环孢素A滴眼液含量测定稳定性

Keywords

cyclosporine AEyedropsQuantitative determinationstability

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