Anesthesia observation of one-lung ventilation to aid HIFU treatment of liver carcinoma

GONG Wenting; et al

doi:10.13406/j.cnki.cyxb.2004.04.025

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Anesthesia observation of one-lung ventilation to aid HIFU treatment of liver carcinoma

更新时间：2024-01-17

- Anesthesia observation of one-lung ventilation to aid HIFU treatment of liver carcinoma
- Journal of Chongqing Medical University Issue 4, Pages: 488-490(2004)
- 作者机构：
  
  1. 重庆医科大学第二临床学院麻醉科
  2. 重庆医科大学第二临床学院麻醉科,重庆,400010
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2004.04.025
  CLC： R735.7
- Published：2004，
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[1]龚文婷,魏安宁,陈玉培,徐昆.单肺通气、人工胸水辅助高强度聚焦超声治疗肝肿瘤的安全性观察[J].重庆医科大学学报,2004(04):488-490.

GONG Wenting, et al. Anesthesia observation of one-lung ventilation to aid HIFU treatment of liver carcinoma. [J]. Journal of Chongqing Medical University (4):488-490(2004)
[1]龚文婷,魏安宁,陈玉培,徐昆.单肺通气、人工胸水辅助高强度聚焦超声治疗肝肿瘤的安全性观察[J].重庆医科大学学报,2004(04):488-490. DOI： 10.13406/j.cnki.cyxb.2004.04.025.

GONG Wenting, et al. Anesthesia observation of one-lung ventilation to aid HIFU treatment of liver carcinoma. [J]. Journal of Chongqing Medical University (4):488-490(2004) DOI： 10.13406/j.cnki.cyxb.2004.04.025.

摘要

目的 :为评估单肺通气、人工胸水隔离肺组织对位于肝脏膈顶部和肝边缘区域肿瘤进行高强度聚焦超声（HIFU）治疗的安全性。方法 :12例肝肿瘤患者在双腔气管插管全麻下

右侧胸腔注入生理盐水形成人工胸水

HIFU治疗时左肺进行10 0 %FiO2 通气。于插管前（Base值）、双肺通气 30min（DLV30 ）、单肺通气（OLV） 15min、30min、6 0min、12 0min

再次双肺通气30min(DLV’30分别抽血气分析 ;持续监测ECG、HR、MAP、SPO2 、PETCO2 ;治疗后 1d、7d胸部X片观察胸水转归。结果 :所有患者在人工胸水单肺通气期间血气和血液动力学各指标均保持稳定。PO2 在双肺和单肺通气期间均高于Base;P分别 <0 .0 1和 0 .0 5

PCO2 、pH均稳定

MAP在DLV30min ;OLV30min、6 0min下降

但在生理正常值范围内 ;人工胸水 7天时各例患者均完全吸收。结论 :单肺通气、人工胸水是协助HIFU治疗肿瘤有效安全的方法

Abstract

Objective:To evaluate the safety of one-lung ventilation and artificial hydrothorax to aid HIFU treatment of liver carcinoma located in distal end of diaphragm and edge of liver and to observe the related indices in the treatment.Methods:Twelve patients with liver carcinoma received general anesthesia using double lumen endobronchial tube bi-chamber trachea cannula.Saline was injected into right thoracic cavity to turn artificial pleural fluid.During HIFU treatment

left lung had a ventilation with 100% FiO

.Before cannula（value of Base）;one lung was ventilated（DLV） for 15 mins

30 mins

60mins

120mins

then double lungs received ventilation again for 30mins（DLV’30）.And blood gas was analyzed separately.Vital monitoring machine kept observing ECG

MAP

and PETCO2.One day and seven days after HIFU

X-ray was made to evaluate the outcome of hydrothorax.Results:All the patients were steady in blood gas and hemodynamic indices at the period of one-lung ventilation with artificial hydrothorax.The indices of PO

were higher during one-or two-lung ventilation than Base （P

0.01 or 0.05）

PCO

and pH were steady.MAP decreased at DLV30min

OLV30min

60min

still being in a normal range.Artificial hydrothorox was absorbed in all patients seven days after injection.Conclusion:One-lung ventilation and artificial hydrothorax can be an aid for a safe and effective HIFU treatment on liver carcinoma.

关键词

肝肿瘤高强度聚焦超声人工胸水单肺通气麻醉

Keywords

Liver carcinomaHigh intensity focused ultrasound(HIFU)Artificial pleural fluidone-lung ventilationanesthesia

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Department of Anesthesiology,the Second Affiliated Hospital,Chongqing Medical University

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重庆医科大学医学超声工程研究所

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