Expression of leukemia inhibitory factor gene of implantation sites and paraimplantation sites from mouse endometrium

YANG Rong; et al

doi:10.13406/j.cnki.cyxb.2004.03.024

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Expression of leukemia inhibitory factor gene of implantation sites and paraimplantation sites from mouse endometrium

更新时间：2024-01-17

- Expression of leukemia inhibitory factor gene of implantation sites and paraimplantation sites from mouse endometrium
- Journal of Chongqing Medical University Issue 3, Pages: 332-333(2004)
- 作者机构：
  
  1. 重庆医科大学生殖医学系
  2. 重庆医科大学生殖医学系,重庆,400016
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2004.03.024
  CLC： R321
- Published：2004，
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[1]杨戎,骆明勇,王应雄,魏莎莉,刘孝云.小鼠子宫内膜胚泡着床点及旁组织白血病抑制因子基因表达研究[J].重庆医科大学学报,2004(03):332-333+350.

YANG Rong, et al. Expression of leukemia inhibitory factor gene of implantation sites and paraimplantation sites from mouse endometrium. [J]. Journal of Chongqing Medical University (3):332-333(2004)
[1]杨戎,骆明勇,王应雄,魏莎莉,刘孝云.小鼠子宫内膜胚泡着床点及旁组织白血病抑制因子基因表达研究[J].重庆医科大学学报,2004(03):332-333+350. DOI： 10.13406/j.cnki.cyxb.2004.03.024.

YANG Rong, et al. Expression of leukemia inhibitory factor gene of implantation sites and paraimplantation sites from mouse endometrium. [J]. Journal of Chongqing Medical University (3):332-333(2004) DOI： 10.13406/j.cnki.cyxb.2004.03.024.

摘要

目的 :探讨白血病抑制因子（LIF）基因在小鼠胚泡着床窗口期了宫内膜表达的特定部位。方法 :采用半定量逆转录聚合酶链反应（RT -PCR）

对 2 0只孕期第 4天的小鼠子宫内膜着床点和旁组织的LIFmRNA进行检测。结果 :2 0只孕期第4天的小鼠着床点LIFmRNA表达平均水平为 0 .5 316

旁组织LIFmRNA表达平均水平为 0 .3711。统计处理t检验差异具有显著性（P <0 .0 5 ）。结论 :在胚泡着床窗口期

小鼠子宫内膜胚泡着床点和旁组织LIF基因表达存在差异。

Abstract

Objective:To investgate the definite spot of expression of leukemia inhibitory factor gene in mouse endometrium in the implantation window phase.Methods:By reverse transcription-polymerase chain reaction(RT-PCR)

the expression of LIF gene of 20 cases of the implantation sites and the paraimplantation sites from the endometrium of the mice that were 4 days pregnant was detected.Results:The average level of LIF mRNA expression of the implantation sites was 0.5316.The average level of LIF mRNA expression of the paraimplantation sites was 0.3711.By the statistic t-test

the difference was significant( P <0.05).Conclusion:In the implantation window phase

the LIF gene expressions of the implantation sites and the paraimplantation sites from the mouse endometrium are different.

关键词

白血病抑制因子子宫内膜着床基因表达

Keywords

Leukemia inhibitory factorendometriumImplantationgene expression

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魏莎莉

杨戎

孟君

马海兰

Related Institution

Department of Genetics, Chongqing Medical University

重庆医科大学遗传优生教研室

重庆市渝中区人口和计划生育生殖健康中心

Department of the Reproductive Physiology,College of Public Health,Chongqing Medical University

Department of Obstetrics and Gynecology,University-Town Hospital of Chongqing Medical University

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