Clinical study on promoting effect of bFGF polypeptide dressings on burn  wound healing

GUO Lei; et al

doi:10.13406/j.cnki.cyxb.2004.01.034

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Clinical study on promoting effect of bFGF polypeptide dressings on burn wound healing

更新时间：2024-01-17

- Clinical study on promoting effect of bFGF polypeptide dressings on burn wound healing
- Journal of Chongqing Medical University Issue 1, Pages: 106-107(2004)
- 作者机构：
  
  1. 重庆医科大学临床学院烧伤整形科
  2. 重庆医科大学临床学院烧伤整形科,重庆,400016
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2004.01.034
  CLC： R644
- Published：2004，
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[1]果磊,贺光照,沈为民.bFGF多肽敷料促进烧伤创面愈合的临床研究[J].重庆医科大学学报,2004(01):106-107.

GUO Lei, et al. Clinical study on promoting effect of bFGF polypeptide dressings on burn wound healing. [J]. Journal of Chongqing Medical University (1):106-107(2004)
[1]果磊,贺光照,沈为民.bFGF多肽敷料促进烧伤创面愈合的临床研究[J].重庆医科大学学报,2004(01):106-107. DOI： 10.13406/j.cnki.cyxb.2004.01.034.

GUO Lei, et al. Clinical study on promoting effect of bFGF polypeptide dressings on burn wound healing. [J]. Journal of Chongqing Medical University (1):106-107(2004) DOI： 10.13406/j.cnki.cyxb.2004.01.034.

摘要

目的 :观察bFGF多肽敷料对浅Ⅱ°烧伤创面的修复作用及可能发生的不良反应。方法 :采用自身对照方法

选择无特殊异常情况的浅Ⅱ°烧伤患者 30例为受试对象

A区为试验创面用无菌多肽敷料、B区为对照创面用无菌生理盐水纱布

观察相同环境中多肽敷料中低浓度的bFGF对浅Ⅱ°烧伤创面是否有加快愈合的作用

并观察其不良反应。结果 :用多肽敷料的A区创面平均愈合日数为 13.0 6± 4 .86天

B区创面平均愈合日数为 15 .36± 4 .97天

A区比B区创面愈合日数明显缩短 ;A区创面分泌物及创周炎明显轻于B区创面 ;两组创面均未发现明显不良反应 ;多肽敷料组总有效率达 10 0 %。结论 :bFGF多肽敷料可促进浅Ⅱ°烧伤创面愈合

缩短愈合时间

使用方便

无明显不良反应

是一种安全、无刺激的理想敷料。

Abstract

Objective:To observe the repairing effects and adverse action of bFGF polypeptide dressings to the superficial second degree burn wounds.Methods:30 superficial second degree burn patients were enrolled in this study.In a self-control study

the trial wounds(A) were applied with polypeptide dressings while the control wounds(B) with the saline gauze dressings to observe the promoting effect of bFGF on the wound healing and the possible adverse action.Results:The average healing time of the trial wounds was 12 days and was 3 days shorter than that of the control wounds.In comparison with control wounds

exudate and local inflammation were slighter on the trial wounds.The effective rate of bFGF polypeptide dressings reached 100%.Conclusion:bFGF polypeptide dressings can promote the healing of superficial second degeree burn wounds and shorten the healing time.This dressing is convenient

safe

non-irritative and has no obvious adverse actions.

关键词

bFGF多肽敷料浅Ⅱ°烧伤创面愈合

Keywords

bFGF polypeptide dressingsSuperficial second degree burnwound healing

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Related Institution

Department of Endocrinology,The Second Affiliated Hospital of Army Medical University

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