The bone marrow studies of 13 children with myelodysplastic syndrome(MDS)

LU Lingling; et al

doi:10.13406/j.cnki.cyxb.2003.06.035

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The bone marrow studies of 13 children with myelodysplastic syndrome(MDS)

更新时间：2024-01-17

- The bone marrow studies of 13 children with myelodysplastic syndrome(MDS)
- Journal of Chongqing Medical University Issue 6, Pages: 797-798(2003)
- 作者机构：
  
  1. 重庆医科大学儿科学院血液科
  2. 重庆医科大学儿科学院血液科,重庆,400014
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2003.06.035
  CLC： R725.5
- Published：2003，
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[1]陆玲玲,刘筱梅,徐酉华.小儿骨髓增生异常综合症(MDS)13例临床分析[J].重庆医科大学学报,2003(06):797-798.

LU Lingling, et al. The bone marrow studies of 13 children with myelodysplastic syndrome(MDS). [J]. Journal of Chongqing Medical University (6):797-798(2003)
[1]陆玲玲,刘筱梅,徐酉华.小儿骨髓增生异常综合症(MDS)13例临床分析[J].重庆医科大学学报,2003(06):797-798. DOI： 10.13406/j.cnki.cyxb.2003.06.035.

LU Lingling, et al. The bone marrow studies of 13 children with myelodysplastic syndrome(MDS). [J]. Journal of Chongqing Medical University (6):797-798(2003) DOI： 10.13406/j.cnki.cyxb.2003.06.035.

摘要

目的 :探讨小儿骨髓增生异常综合症（MDS）的实验室检查特征及临床特点。方法 :对 13例诊断为MDS患儿的外周血、骨髓像及临床表现进行回顾性分析。结果 :13例患儿 11例为男性

2例女性。临床以发热、贫血、肝脾肿大为主要表现。13例患儿均为中重度贫血

外周血见有核红细胞

白细胞表现为增高、正常或减低。 4例患儿外周血见幼稚细胞

血小板可正常或减低

网织红细胞多数偏高。骨髓均增生活跃

有红系或粒系病态造血

以巨幼样改变为主 ;诊断为RA10例

RAEB2例

RAEB -t1例。结论 :小儿MDS诊断仍主要靠骨髓检查

骨髓至少一系出现病态造血

巨幼样改变较易见

并除外其他引起病态造血的疾病

需注意和再障相鉴别。

Abstract

Objective:Discussing the laboratory findings and clinical features of the children with MDS.Methods:Analysing the results of peripheral blood

bone marrow and clinical manifestations in 13 patients with MDS.Results:All 13 patients were male.Main clinical manifestations include fever

anemia and hepatosplenomegaly.The anemia was of moderate to severe degree.Immature RBC were found in the peripheral blood smears.WBC ranged from high

normal or low.Immature peripheral blood cells were seen in 4 patients.The counts of platelets were normal or low.The bone marrow showed hyperplasia actively and abnormal erythropoiesis and/or myelopoiesis.The diagnosis in 10 patients was RA

2 patients

RAEB and 1 patient

RAEB-t.Conclusion:The diagnosis of MDS depends on the bone marrow examination.The bone marrow shows one abnormal hematopoietic system at least and must differentiate with other hematologic disorders.

关键词

骨髓增生异常综合症儿童骨髓临床分析

Keywords

Myelodysplastic syndromechildrenBone marrowclinical analysis

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