Therapeutic effects of compound naftifine cream on experimental dermatophytosis in guinea pigs

LI Anrong; et al

doi:10.13406/j.cnki.cyxb.2003.05.026

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Therapeutic effects of compound naftifine cream on experimental dermatophytosis in guinea pigs

更新时间：2024-01-17

- Therapeutic effects of compound naftifine cream on experimental dermatophytosis in guinea pigs
- Journal of Chongqing Medical University Issue 5, Pages: 633-635(2003)
- 作者机构：
  
  1. 重庆医科大学临床学院药剂科
  2. 重庆医科大学临床学院药剂科,重庆,400016
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2003.05.026
  CLC： R969
- Published：2003，
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[1]李安荣,江舟,王体强,毛郴.复方萘替芬霜治疗豚鼠须癣毛癣菌及白念珠菌感染的疗效观察[J].重庆医科大学学报,2003(05):633-635.

LI Anrong, et al. Therapeutic effects of compound naftifine cream on experimental dermatophytosis in guinea pigs. [J]. Journal of Chongqing Medical University (5):633-635(2003)
[1]李安荣,江舟,王体强,毛郴.复方萘替芬霜治疗豚鼠须癣毛癣菌及白念珠菌感染的疗效观察[J].重庆医科大学学报,2003(05):633-635. DOI： 10.13406/j.cnki.cyxb.2003.05.026.

LI Anrong, et al. Therapeutic effects of compound naftifine cream on experimental dermatophytosis in guinea pigs. [J]. Journal of Chongqing Medical University (5):633-635(2003) DOI： 10.13406/j.cnki.cyxb.2003.05.026.

摘要

目的 :观察复方萘替芬霜治疗豚鼠皮肤须癣毛癣菌及白念珠菌感染的疗效。方法 :皮肤须癣毛癣菌及白念珠菌感染的动物模型各 6 0只

分别分为 6组

分别外用 2 .5 %、1.2 5 %和 0 .6 2 5 %复方萘替芬霜剂和 0 .5 %酮康唑霜与 2 %萘替芬霜和空白赋形剂

治疗疗程 14天。结果 :复方萘替芬霜疗效均较酮康唑霜、茶替芬霜和空白赋形剂优（P <0 .0 1）。结论 :复方萘替芬霜剂治疗豚鼠须癣毛癣茵及白念珠菌均有较高的疗效。

Abstract

Objective:To evaluate the therapeutic effects of compound naftifine cream on experimental dermatophytosis caused by trichophyton purpureatum or candida albicans.Methods:Two dermatophytosis models of 120 guinea pigs were made and divided into 6 groups( n =10) respectively.Topically 2.5%

1.25%

0.625% of compound naftifine cream and 0.5% cream ketoconazole and 2% cream naftifine and control agent were used in all laboratory animals respectively.All were used for 14days.Results:The efficacy of the compound naftifine cream in topically administered animals was better than that in the ketoconazole or nafiifine cream treatment groups ( P <0.01) respectively.Conclusion:The compound naftifine cream topically used in the treatment of dermatophytosis can be permitted.

关键词

萘替芬酮康唑须癣毛癣菌白念珠菌霜剂

Keywords

NaftifineKetoconazoleCandida albicansTrichophyton purpureatumCream

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