Effect of hydrotalcid combined with Tibolone on the bile reflux gastritis and intragastric bile in the menopause patients with bilereflux gastritis

GU Sai; et al

doi:10.13406/j.cnki.cyxb.2003.03.018

您当前的位置：

首页 >

文章列表页 >

Effect of hydrotalcid combined with Tibolone on the bile reflux gastritis and intragastric bile in the menopause patients with bilereflux gastritis

更新时间：2024-01-17

- Effect of hydrotalcid combined with Tibolone on the bile reflux gastritis and intragastric bile in the menopause patients with bilereflux gastritis
- Journal of Chongqing Medical University Issue 3, Pages: 316-318(2003)
- 作者机构：
  
  1. 重庆医科大学临床学院消化内科
  2. 重庆医科大学临床学院消化内科,重庆,400016
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2003.03.018
  CLC： R573.3
- Published：2003，
扫描看全文
[1]古赛,唐承薇,刘纯伦.铝碳酸镁联合女性激素对绝经期妇女胆汁反流性胃炎疗效及胃内胆汁的影响[J].重庆医科大学学报,2003(03):316-318.

GU Sai, et al. Effect of hydrotalcid combined with Tibolone on the bile reflux gastritis and intragastric bile in the menopause patients with bilereflux gastritis. [J]. Journal of Chongqing Medical University (3):316-318(2003)
[1]古赛,唐承薇,刘纯伦.铝碳酸镁联合女性激素对绝经期妇女胆汁反流性胃炎疗效及胃内胆汁的影响[J].重庆医科大学学报,2003(03):316-318. DOI： 10.13406/j.cnki.cyxb.2003.03.018.

GU Sai, et al. Effect of hydrotalcid combined with Tibolone on the bile reflux gastritis and intragastric bile in the menopause patients with bilereflux gastritis. [J]. Journal of Chongqing Medical University (3):316-318(2003) DOI： 10.13406/j.cnki.cyxb.2003.03.018.

摘要

目的 :探讨铝碳酸镁联合替勃龙（小剂量雌孕雄激素）对绝经期妇女胆汁反流性胃炎的疗效及胃内胆汁的影响。方法 :19例绝经期妇女

有烧心、上腹饱胀、恶心、呕吐胆汁等症状

均经胃镜证实为胆汁反流性胃炎

胃内 2 4h胆汁监测证实有胆汁反流。随机分为 2组

一组服铝碳酸镁

1g/次

3次 /天

另一组服替勃龙 2 .5mg/次 /天 +铝碳酸镁（剂量同前）

疗程 4周。观察治疗前后上述症状及胃内胆汁变化。结果 :两组治疗后各项症状均有改善

并随时间延长改善率提高

铝碳酸镁联合替勃龙改善症状优于单用铝碳酸镁。两组治疗前后 2 4h胃内胆汁监测

除反流次数无明显减少外

长反流次数、最长反流时间、反流总时间百分比均较治疗前明显下降（P <0 .0 5 ）

两组之间治疗后比较各项指标无显著性差异。结论 :铝碳酸镁联合小剂量雌孕雄激素能有效缓解绝经期妇女胆汁反流性胃炎症状

减少胃内胆汁反流

为治疗绝经期胆汁反流性胃炎的良好方案。

Abstract

Objective:To evaluate the effect of hydrotalcid combined with Tibolone

a compound with the effects of estrogen

progestogen and androgen on the menopause patients with bile-reflux gastritis and 24-hour intragastric bile.Methods:Nineteen menopause women with bile-reflux gastritis proven by gastroscope and 24-hour intragastric bile monitoring were divided into 2 groups at random

which were treated with hydtotalcid 1.0g three times a day and the same dose of hydrotalcid combined with Tibolone 2.5mg one time a day.The severity of the symptoms including heartburn

epigastric distention

nausea and bile vomiting was investigated before and after 2

4 weeks treatment.Twenty-four hour intragastrie bile monitoring was also reexamined.Results:The severity of all the symptoms in the two groups decreased greatly after 2 weeks treatment.After 4 weeks treatment

the severity of all the symptoms decreased further.The total fraction time of bile reflux

the time of the longest bile reflux in two groups decreased greatly after treatment ( P <0.05).Conclusion:Hydrotalcid combined with Tibolone can release the symptoms of bile reflux gastritis of menopause women with functional dyspepsia and decreased the index of 24 hour intragastric bile monitcring

and it is an effectire treatment program for the menopause women with bile reflux gastritis.

关键词

胆汁反流性胃炎绝经期铝碳酸镁替勃龙

Keywords

Bile reflux gastritisMenopauseHydrotalcidTibolone

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Combination of tibolone and cisapride promoted gallbladder emptying in menopause patients with functional dyspepsia

Tibolone relieves the symptoms of functional dyspepsia in menopausal women

Research for risk factor of endometial hyperplasia and endometrial cancer

Related Author

GU Sai

et al

钟晓明

黄晓玲

GU Sai

et al

GONG Zhu-ping

et al

Related Institution

重庆医科大学临床学院超声科

Chongqing Health Centen for Women and Childen

⁰