The biomechanical strengthening effect of percutaneous vertebroplasty

DENG Zhongliang; et al

doi:10.13406/j.cnki.cyxb.2003.02.028

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The biomechanical strengthening effect of percutaneous vertebroplasty

更新时间：2024-01-17

- The biomechanical strengthening effect of percutaneous vertebroplasty
- Journal of Chongqing Medical University Issue 2, Pages: 208-209(2003)
- 作者机构：
  
  1. 重庆医科大学第二临床学院骨科
  2. 重庆医科大学第二临床学院骨科,重庆,400010
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2003.02.028
  CLC： R687.3
- Published：2003，
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[1]邓忠良,程昀,赵大渝,黄朝梁,周言忠.经皮穿刺椎体成形术的体外力学性能研究[J].重庆医科大学学报,2003(02):208-209+212.

DENG Zhongliang, et al. The biomechanical strengthening effect of percutaneous vertebroplasty. [J]. Journal of Chongqing Medical University (2):208-209(2003)
[1]邓忠良,程昀,赵大渝,黄朝梁,周言忠.经皮穿刺椎体成形术的体外力学性能研究[J].重庆医科大学学报,2003(02):208-209+212. DOI： 10.13406/j.cnki.cyxb.2003.02.028.

DENG Zhongliang, et al. The biomechanical strengthening effect of percutaneous vertebroplasty. [J]. Journal of Chongqing Medical University (2):208-209(2003) DOI： 10.13406/j.cnki.cyxb.2003.02.028.

摘要

目的 :探讨经皮椎体成形术对椎体力学强度的影响作用。方法 :4具完整老年女性胸腰段脊柱（T11-L2 ）

X线摄片无明显病理异常

用DEXA测定脊柱骨密度BMD

将标本游离成单个椎体

将每例标本的 4个椎体随机选择 2个共 8个椎体进行骨水泥PMMA注射构成椎体成形术组（A组）

余 8个椎体为对照组（B组）。A组行椎体成形术注射加显影剂的低粘度骨水泥 5ml。注射后摄轴位X线片了解骨水泥分布情况。测试A组和B组椎体静态压缩下的最大抗压强度及刚度。结果 :所有椎体BMD的T值提示为中重度骨质疏松（T值 - 3.15～ - 4 .6 6

平均 - 3.87）。A组注射 5ml骨水泥后轴位片示骨水泥分布面积皆大于 5 0 %。A组的最大抗压强度和刚度分别为 2 6 4 5± 4 78N和 1317± 2 81N/mm ;B组最大抗压强度 186 2± 6 2 0N

刚度为 10 2 5± 2 33N/mm。两组比较最大抗压强度及刚度均存在显著性差异（P <0 .0 5 ）。结论 :骨质疏松椎体内注射骨水PMMA可显著改善其力学性能

临床应用经皮椎体成形术可达到强化椎体的目的。

Abstract

Objective: To examine whether percutaneous vertebroplasty is effective in biomechanical strengthening vertebral body. Methods:Four vertebral bodies (T 11 -L 2) from each of four fresh spines were harvested from female cadavers (age

70±5 years)

screened for BMD using DEXA and separated into individual vertebral bodies.Two vertebrae of each set were selected at random to be vertebroplasty group (Group A

n=8);others were control group (Group B

n=8).Each vertebra of Group A was injected with 5 ml low viscosity polymethylmethacrylate (PMMA) using transpedicular approach.The strength and stiffness of these vertebral bodies were measured. Results: The BMD indicated two group vertebral bodies suffered from serious osteoporosis (T=-3.15 to -4.66).The strength and stiffness were 2645±478N and 1317±281N/mm in group A;1862±620N and 1025±233N/mm in group B.Vertebral body strength of group A after injection of PMMA was stronger than that of group B ( P <0.05). Conclusion: Injection of PMMA using percutaneous vertebroplasty technique appeared to have strengthened osteoporotic vertebral bodies.

关键词

经皮穿刺椎体成形术骨水泥椎体压缩强度

Keywords

percutaneous vertebroplastyBone cementVertebral bodyCompression strength

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Related Institution

Department of Orthopaedics, the Second College of Clinical Medicine, Chongqing Medical University

Department of Orthopedic，the Second Affiliated Hospital，Chongqing Medical University

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