Study on the relativity of the oxidative stress and the serum copper of carcinoma of nasopharynx patients

LI Bing; et al

doi:10.13406/j.cnki.cyxb.2003.02.018

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Study on the relativity of the oxidative stress and the serum copper of carcinoma of nasopharynx patients

更新时间：2024-01-17

- Study on the relativity of the oxidative stress and the serum copper of carcinoma of nasopharynx patients
- Journal of Chongqing Medical University Issue 2, Pages: 179-180(2003)
- 作者机构：
  
  1. 重庆医科大学临床学院耳鼻喉科
  2. 四川省隆昌县人民医院
  3. 重庆医科大学基础医学院,重庆,400016
  4. 隆昌,642150
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2003.02.018
  CLC： R739.63
- Published：2003，
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[1]李兵,范贤勇,俸家富,李少林.鼻咽癌患者血清铜与氧化应激反应的相关性研究[J].重庆医科大学学报,2003(02):179-180+219.

LI Bing, et al. Study on the relativity of the oxidative stress and the serum copper of carcinoma of nasopharynx patients. [J]. Journal of Chongqing Medical University (2):179-180(2003)
[1]李兵,范贤勇,俸家富,李少林.鼻咽癌患者血清铜与氧化应激反应的相关性研究[J].重庆医科大学学报,2003(02):179-180+219. DOI： 10.13406/j.cnki.cyxb.2003.02.018.

LI Bing, et al. Study on the relativity of the oxidative stress and the serum copper of carcinoma of nasopharynx patients. [J]. Journal of Chongqing Medical University (2):179-180(2003) DOI： 10.13406/j.cnki.cyxb.2003.02.018.

摘要

目的 :探讨鼻咽癌患者血清铜（Cu）与氧化应激反应的相关性。方法 :测定 111例鼻咽癌患者和 36例健康对照者血清铜（Cu）、铜蓝蛋白（CER）及丙二醛（MDA）浓度

并进行对比分析。结果 :鼻咽癌患者脂质过氧化水平明显高于对照组（P <0 .0 0 1） ;铜蓝蛋白（CER）明显升高（P <0 .0 2 ） ;血清铜浓度明显升高（P <0 .0 0 1） ;血清Cu和丙二醛呈明显相关性（γ =0 .2 81

P =0 .0 0 3）。结论 :鼻咽癌患者血清微量元素铜（Cu）与氧化应激反应呈正相关。

Abstract

Objective: To investigate the relativity of the oxidative stress and the serum copper of the carcinoma of nasopharynx(NPC) patients.Methods: The concentration of serum copper

CER and MDA of 111 cases of NPC patients was detected and compared with control group. Results:The study showed that the serum MDA of the patients was significantly increased than the control ( P <0.001);the serum CER concentration was significantly higher in the NPC patients ( P <0.02);and the serum copper level was significantly increased than the control ( P <0.001). Conclusion: The oxidative stress of NPC is related to the trace element.

关键词

鼻咽癌氧化应激微量元素

Keywords

Carcinoma of nasopharynxoxidative stresstrace element

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