Study on the separated cultivation and drug sensitivity of respiratory  tract fastidious bacteria in chidren

LIU Lan; et al

doi:10.13406/j.cnki.cyxb.2003.02.014

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Study on the separated cultivation and drug sensitivity of respiratory tract fastidious bacteria in chidren

更新时间：2024-01-17

- Study on the separated cultivation and drug sensitivity of respiratory tract fastidious bacteria in chidren
- Journal of Chongqing Medical University Issue 2, Pages: 166-168(2003)
- 作者机构：
  
  1. 重庆医科大学儿科学院检验科
  2. 重庆医科大学儿科学院检验科,重庆,400014
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2003.02.014
  CLC： R446.5
- Published：2003，
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[1]刘岚,刘昌林,朱军.儿童呼吸道苛养菌分离培养及药敏分析[J].重庆医科大学学报,2003(02):166-168.

LIU Lan, et al. Study on the separated cultivation and drug sensitivity of respiratory tract fastidious bacteria in chidren. [J]. Journal of Chongqing Medical University (2):166-168(2003)
[1]刘岚,刘昌林,朱军.儿童呼吸道苛养菌分离培养及药敏分析[J].重庆医科大学学报,2003(02):166-168. DOI： 10.13406/j.cnki.cyxb.2003.02.014.

LIU Lan, et al. Study on the separated cultivation and drug sensitivity of respiratory tract fastidious bacteria in chidren. [J]. Journal of Chongqing Medical University (2):166-168(2003) DOI： 10.13406/j.cnki.cyxb.2003.02.014.

摘要

目的 :分析儿童呼吸道苛养菌的感染率及常用抗生素的耐药状况。方法 :采用儿童呼吸道 2 0 5 0份咽拭子及痰标本进行苛养菌分离培养与鉴定

并对其中 6 17株苛养菌做了药敏试验。结果 :显示 2 75株肺炎链球菌

耐药率较高的有红霉素81.1%、苯唑西林 76 .9%、复方磺胺甲口恶唑 76 .9%、四环素 6 5 .4 % ;10 4株流感嗜血杆菌、184株副流感嗜血杆菌、5 4株卡他莫拉菌对氨苄西林耐药率分别为 17.6 %、2 8.9%、6 4 .9%

对亚胺培南 /西司他丁耐药率分别为 16 .4 %、16 .5 %、0

同时复方磺胺甲口恶唑的耐药率也分别高达 5 6 .7%、5 6 .7%、6 4 .9%。结论 :提示苛养菌在儿童呼吸道感染中占有重要的地位

及时掌握这类细菌的耐药动态

对合理使用抗生素、延缓耐药株的产生有极其重要的临床意义。

Abstract

Objective:To analyse the infection rate and antibiotic susceptibility of respiratory tract fastidious bacteria in children. Method: The fastidious bacteria were isolated and identified which came from the pharynx-swabs and sputum specimen.2050 in total.of children′s repiratory tracts.Furthermore

the drug sensitirity tests were done on 617 strains of them.Results: The resistance rates of streptococcus Pneumoniae(275 strains) to erythromycin

oxacillin

SMZ-co and tetracycline were 81.1%

76.9%

65.4%

respectively.The resistance rates of H influenzae(104 strains)

H parainfluenzae(184 strains)

M catarrhalis(54 strains) to ampicillin were 17.6%

28.9%

64.9%

respectively;to imipenem/cilastatin were 16.4%

16.5%

0;respectively;to SMZ-TMP were 56.7%

56.7%

64.9%

respectively; Conclusion: Fastidious bacteria possess a very important position in children′s respiratory tract infection.In order to use antibiotics reasonably and postpone the drug resistance

it is necessary to control the development of drug resistance of fastidious bacteria.This is important to the clinical use of antibiotics.

关键词

儿童呼吸道苛养菌体外药敏试验

Keywords

childrenrespiratory tractFastidious bacteriaDrug sensitivitg test

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Related Institution

Department of Biochemistry and Molecular Biology,School of Basic Medicine,Ningxia Medical University

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Department of Endocrinology， Guangdong Provincial People’s Hospital，Guangdong Academy of Medical;Sciences

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