The histomorphological study of the expanded polytetrafluoroethylene  patch transplanted to abdominal aorta of dogs

HUANG Wen; et al

doi:10.13406/j.cnki.cyxb.2003.02.007

您当前的位置：

首页 >

文章列表页 >

The histomorphological study of the expanded polytetrafluoroethylene patch transplanted to abdominal aorta of dogs

更新时间：2024-01-17

- The histomorphological study of the expanded polytetrafluoroethylene patch transplanted to abdominal aorta of dogs
- Journal of Chongqing Medical University Issue 2, Pages: 144-146(2003)
- 作者机构：
  
  1. 重庆医科大学临床学院血管外科研究室
  2. 重庆医科大学临床学院血管外科研究室,重庆,400016
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2003.02.007
  CLC： R654.2
- Published：2003，
扫描看全文
[1]黄文,时德,赵瑜.犬膨体聚四氟乙烯人工血管补片移植后的组织形态学研究[J].重庆医科大学学报,2003(02):144-146.

HUANG Wen, et al. The histomorphological study of the expanded polytetrafluoroethylene patch transplanted to abdominal aorta of dogs. [J]. Journal of Chongqing Medical University (2):144-146(2003)
[1]黄文,时德,赵瑜.犬膨体聚四氟乙烯人工血管补片移植后的组织形态学研究[J].重庆医科大学学报,2003(02):144-146. DOI： 10.13406/j.cnki.cyxb.2003.02.007.

HUANG Wen, et al. The histomorphological study of the expanded polytetrafluoroethylene patch transplanted to abdominal aorta of dogs. [J]. Journal of Chongqing Medical University (2):144-146(2003) DOI： 10.13406/j.cnki.cyxb.2003.02.007.

摘要

目的 :观察犬膨体聚四氟乙烯人工血管补片移植

在不同时期的组织形态学变化。方法 :用e -PTFE补片修补 16条犬的腹主动脉

在植入后 2、4、8、12、2 0、2 8周采集标本

作光镜、扫描及透射电镜观察。结果 :①内皮细胞 2周已在材料上出现

8周时完全覆盖材料面 ;②内膜增生主要是平滑肌细胞和胶原纤维增生 ;③在 8周以前内膜增厚较快

12周以后逐趋缓和 ;④补片与血管吻合处增生明显 ;⑤增生的内膜容易与材料分离。结论 :内皮细胞可以覆盖e -PTFE材料表面

其内膜增生主要是平滑肌细胞和胶原纤维增生引起 ;主要原因可能是内皮细胞慢性损伤

血小板聚集

血流动力学改变

材料与血管顺应性不一致等。

Abstract

Objective:To observe the cell coverage of the e-PTFE patch

the cellular proliferation and morphologic change of neointima. Methods: Sixteen dogs′ abdominal aorta repaired by e-PTFE patches were taken as specimens at 2

28 week after implantation

and the specimens were observed by light microscope

scanning electron microscope and transmission electron microscope. Results: ①Endothelial cells began to appear on the surface of e-PTFE patch at the second week and covered the entire patch surface at the eighth week.②Smooth muscle cell and collagen fibers formed intimal hyperplasia.③The intimal thickening was fast before eight week

but slow after twelve week.④The cells at the anastomotic site continued to proliferate.⑤The neointima over e-PTFE was easy to separate from the material. Conclusion: These results indicate that endothelial cells can cover the surface of e-PTFE patch.The intimal thickening is caused by the proliferation of the smooth muscle cell and collagen.The proliferation might be due to chronic endothelial cell injury

platelet accumulation

hemodynamic change and graft-artery compliance mismatch.

关键词

膨体聚四氟乙烯重建人工血管组织形态学

Keywords

Expanded polytetrafluoroethylenereconstructionVascular prosthesisHistomorphology

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Comparative evaluation of expanded polytetrafluoroethylene and polypropylene mesh used for repair of abdominal wall defect in rats

Biomechanical study of fixation stability with anterior approach screw fixation through C₂ vertebral body to C₁ lateral mass and Gallie’s technique

Application value of low-dose CT scanning in esophageal foreign body

Establishment and validation of the three dimensional finite element model of atlantoaxial vertebra

Impacted bone graft combined with structural bone graft for the reconstruction of acetabular bone defects in adult developmental dysplasia of hip

Related Author

et al

PU Qing-hua

欧云生

et al

GUO Liang

杨伟江

罗焕江

et al

Related Institution

Department of Surgery, College of Clinical Medicine .Chongqing Medical University

重庆医科大学临床学院普外科

Department of Orthopdics,the First Affiliated Hospital,Chongqing Medical University

Department of Radiology,the Fourth Affiliated Hospital,Guangxi Medical University

Department of Orthopdicst,he First Affiliated Hospital,Chongqing Medical University

⁰