Observation of clinical efficacy on treating urticaria with desloratadine and loratadine

ZHOU Xun; et al

doi:10.13406/j.cnki.cyxb.2003.01.024

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Observation of clinical efficacy on treating urticaria with desloratadine and loratadine

更新时间：2024-01-17

- Observation of clinical efficacy on treating urticaria with desloratadine and loratadine
- Journal of Chongqing Medical University Issue 1, Pages: 78-79(2003)
- 作者机构：
  
  1. 重庆医科大学临床学院皮肤科
  2. 重庆医科大学临床学院皮肤科,重庆,400016
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.2003.01.024
  CLC： R758.24
- Published：2003，
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[1]周汛,李惠,王娟.地洛他定与氯雷他定治疗荨麻疹临床对比观察[J].重庆医科大学学报,2003(01):78-79+89.

ZHOU Xun, et al. Observation of clinical efficacy on treating urticaria with desloratadine and loratadine. [J]. Journal of Chongqing Medical University (1):78-79(2003)
[1]周汛,李惠,王娟.地洛他定与氯雷他定治疗荨麻疹临床对比观察[J].重庆医科大学学报,2003(01):78-79+89. DOI： 10.13406/j.cnki.cyxb.2003.01.024.

ZHOU Xun, et al. Observation of clinical efficacy on treating urticaria with desloratadine and loratadine. [J]. Journal of Chongqing Medical University (1):78-79(2003) DOI： 10.13406/j.cnki.cyxb.2003.01.024.

摘要

目的:评价地洛他定治疗荨麻疹的疗效和安全性。方法:将 50例荨麻疹患者随机分为试验组地洛他定5mgl日1次和对照组氯雷他定10mgl日1次

疗程均为7天（急性荨麻疹）或14天（慢性荨麻疹）。结果:治疗组与对照组在起效时间及疗效比较无显著性差异（P=0.971和P=0.051）。两组病例不良反应相似且轻微。结论:地洛他定是治疗荨麻疹安全有效的药物。

Abstract

Objective:To evalute the efficacy and safty of desloratadine against urticaria. Methods: Fifty patients with urticaria were randomly assigned to receive either 5mg of desloratadine daily or lOmg of loratadine daily for 7 days (acute urticaria) and 14 days (chronic urticaria). Results : There were no statistically significant differences between the two groups in terms of time in taking effect and clinical efficacy(P = 0.971 and P = 0.051). Adverse effects were similar and mild in the two groups. Conclusion :It is indicated that desloratadine is well - tolerated and effecitive for the treatment of urticaria.

关键词

荨麻疹地洛他定氯雷他定

Keywords

urticariaDesloratadineLoratadine

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Related Institution

Department of Pharmacy,College of Clinical Medicine, Chongqing Medical University

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Department of Otolaryngology,College of Clinical Medicine,Chongqing Medical University

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Department of Dermatology,the First Affiliated Hospital,Chongqing Medical University

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